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Research article summary:
Verbal learning in Alzheimers dementia.
Abstract Extract:
Many recent findings in Western countries suggest that episodic recall is the most sensitive discriminator between patients with mild Alzheimer disease (AD) and the normal elderly, while semantic memory tends best to differentiate between moderate and ... (Full abstract text below) Published 2003Mar
in Journal: J Int Neuropsychol Soc
(Language : eng)
Full Pubmed Extract
This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:
1. J Int Neuropsychol Soc.
2003 Mar;9(3):363-75
Verbal learning in Alzheimer's dementia.
Au A, Chan AS, Chiu H
Department of Clinical Psychology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China. auml@ha.org.hk
Many recent findings in Western countries suggest that episodic recall is the most sensitive discriminator between patients with mild Alzheimer disease (AD) and the normal elderly, while semantic memory tends best to differentiate between moderate and severe AD patients. The present study is the first to examine in detail the episodic memory of Chinese AD patients in Hong Kong with a locally developed list learning test, comparing procedures that do or do not encourage the use of semantic organization. The performance of 28 AD patients was compared to that of 30 normal controls. AD patients did significantly worse in terms of acquisition and retention and also benefited significantly less from external organization cues. In the discriminant function analysis, the rate of forgetting in the random condition and the total retention score in the blocked condition were found to be the best predictors for differentiating between AD patients and controls. On the other hand, in the differentiation between mild and moderate AD, semantic clustering in the blocked condition was found to be the best predictor. Results of the present study were discussed in the light of the previous findings reported in the Western countries and the neuropathological changes of AD patients.
PMID : 12666761 [PubMed - Indexed for MEDLINE]
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Full Author Information
| First Name | LastName | Initials |
| Alma | Au | A |
| Agnes S | Chan | AS |
| Helen | Chiu | H |
Affiliation: Department of Clinical Psychology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China. auml@ha.org.hk
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