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| Research article summary (published 30 Jan 2002): |
Utility of the WHO neurobehavioral core test battery in Chinese workers-a meta-analysis.
Full Abstract
We performed a meta-analysis to determine the most sensitive subtests of the WHO Neurobehavioral Core Test Battery (NCTB) when administered to Chinese workers. Extensive Chinese Biological Medical Database and MEDLINE searches, review of cited references, and discussion with other investigators were undertaken. Data were extracted from 39 eligible studies; the summary effects (effect sizes) were calculated using a fixed-effect model. Various exposure agents showed different sensitivities to the seven subtests of NCTB. For mercury-exposure, the Benton Visual Retention was the most sensitive subtest, with an effect size (95% CI) of 6.0 (4.4-7.6). For lead-exposure, the most sensitive subtests were the Pursuit Aiming II and Profile of Mood States, with effect sizes (95% CI) of 11.3 (8.3-14.3) and 10.6 (7.5-13.7), respectively. For organic solvents-exposure, Digit Span, Pursuit Aiming II, and Digit Symbol were the most sensitive subtests, with effect sizes (95- CI) of 4.7 (3.3-6.1), 4.6 (3.1-6.1), and 4.1 (2.7-5.5), respectively.
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Author information
Author/s: Zhou, Wei (W); Liang, Youxin (Y); Christiani, David C (DC);
Affiliation: Department of Environmental Health, Harvard School of Public Health, Occupational Health Program, 665 Huntington Avenue, Boston, Massachusetts, 02115, USA.
Grants: ES00002 (Agency:United States NIEHS) ; TW00828 (Agency:United States FIC)
Journal and publication information
Publication Type: Journal Article; Meta-Analysis; Research Support, U.S. Gov't, P.H.S.
Journal: Environmental research (Environ Res), published in United States. (Language: eng)
Reference: 2002-Feb; vol 88 (issue 2) : pp 94-102
Dates: Created 2002/03/22; Completed 2002/04/30; Revised 2007/11/14;
PMID: 11908934, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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