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| Research article summary (published 30 Dec 2002): |
Syntactic comprehension in Parkinson's disease: investigating early automatic and late integrational processes using event-related brain potentials.
Full Abstract
Parkinson's disease (PD) has been associated with a general impairment of procedures and with an impairment of syntactic procedures in particular. The present study investigated comprehension processes in PD using event-related brain potentials (ERPs). PD patients and controls listened to sentences that were either correct or syntactically or semantically incorrect. The language-related ERP component correlated with semantic processes (N400) was present in both groups. In the syntactic domain, early automatic processes (early negativity) appeared normal in PD, whereas late integrational processes (P600) were modulated by this disease. The present findings suggest that the basal ganglia primarily do not support early automatic syntactic processes during comprehension but rather support processes of syntactic integration.
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Author information
Author/s: Friederici, Angela D (AD); Kotz, Sonja A (SA); Werheid, Katja (K); Hein, Grit (G); von Cramon, D Yves (DY);
Affiliation: Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany. angelafr@cns.mpg.de
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Neuropsychology (Neuropsychology), published in United States. (Language: eng)
Reference: 2003-Jan; vol 17 (issue 1) : pp 133-42
Dates: Created 2003/02/24; Completed 2003/04/11; Revised 2006/11/15;
PMID: 12597082, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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