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| Research article summary (published 30 Dec 2002): |
A summary of results of the Dietary Intervention Study in Children (DISC): lessons learned.
Full Abstract
Prevention of cardiovascular disease must begin in childhood, preferably before risk factors develop. Elevated low-density lipoprotein cholesterol levels in children are likely to track over time and become high-risk levels in adults. The Dietary Intervention Study in Children (DISC) was a multicenter, collaborative randomized trial in pre-adolescent children designed to test the efficacy and safety of a dietary intervention to lower saturated fat and cholesterol intake among growing children with elevated low-density lipoprotein cholesterol. Numerous DISC results, which include findings on lipids-lipoproteins, genetics, and nutrient adequacy, as well as descriptions of the behavioral intervention strategies, have been reported. A summary of practical findings and their potential clinical applications have not previously been published. Highlights of key lessons learned from DISC and translational applications of potential interest to nurses and other health care providers are presented.Copyright 2003 CHF, Inc.
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Author information
Author/s: Van Horn, Linda (L); Obarzanek, Eva (E); Barton, Bruce A (BA); Stevens, Victor J (VJ); Kwiterovich, Peter O (PO); Lasser, Norman L (NL); Robson, Alan M (AM); Franklin, Frank A (FA); Lauer, Ronald M (RM); Kimm, Sue Y S (SY); Dorgan, Joanne F (JF); Greenlick, Merwyn R (MR);
Affiliation: Department of Preventive Medicine, Northwestern University Medical School, 680 North Lake Shore Drive, #1102, Chicago, IL 60611, USA. LVanhorn@Northwestern.edu
Journal and publication information
Publication Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal: Progress in cardiovascular nursing (Prog Cardiovasc Nurs), published in United States. (Language: eng)
Reference: 2003-; vol 18 (issue 1) : pp 28-41
Dates: Created 2003/03/07; Completed 2003/05/15; Revised 2006/11/15;
PMID: 12624570, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
Comments and Corrections
CommentIn: Prog Cardiovasc Nurs. 2003 Winter;18(1):4-5. (PMID: 12624566)
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