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| Research article summary (published 30 Aug 2002): |
Subjective and objective neuropsychological abnormalities in a psychosis prodrome clinic.
Full Abstract
BACKGROUND:
Predicting transitions to psychosis is difficult. Neuropsychology might facilitate predictions.
AIMS:
To report preliminary data on self-perceived and objectively measurable neurocognition in prodromal patients of the first German early recognition centre.
METHOD:
Subjective neuropsychological disturbances were assessed in 51 patients with potentially prodromal symptoms of schizophrenia. Initial neurocognitive functioning was compared with matched normals and patients with schizophrenia.
RESULTS:
Self-perceived deficits mostly concerned perception, cognition and stress reactivity. Five transitions happened during the 15-month follow-up. Recently emerging or intensifying deficits were to some extent predictive of transition. Persons at risk performed worse than controls on objectively measured verbal capacity, attention and memory functions.
CONCLUSIONS:
Neuropsychological deficits, either self-perceived or objectively measured, characterise persons at risk for schizophrenia and may contribute to predicting transitions.
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Author information
Author/s: Hambrecht, Martin (M); Lammertink, Michael (M); Klosterkötter, Joachim (J); Matuschek, Eveline (E); Pukrop, Ralf (R);
Affiliation: Department of Psychiatry and Psychotherapy, University of Cologne, Germany. hambrecht.martin@krankenhaus-elisabethenstift.de
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: The British journal of psychiatry. Supplement (Br J Psychiatry Suppl), published in England. (Language: eng)
Reference: 2002-Sep; vol 43 (issue ) : pp s30-7
Dates: Created 2002/09/25; Completed 2002/11/22; Revised 2008/02/22;
PMID: 12271798, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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