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| Research article summary (published 29 Apr 2002): |
Studies of altered social cognition in neuropsychiatric disorders using functional neuroimaging.
Full Abstract
In this paper, we review studies using functional neuroimaging to examine cognition in neuropsychiatric disorders. The focus is on social cognition, which is a topic that has received increasing attention over the past few years. A network of brain regions is proposed for social cognition that includes regions involved in processes relevant to social functioning (for example, self reference and emotion). We discuss the alterations of activity in these areas in patients with autism, depression, schizophrenia, and posttraumatic stress disorders in relation to deficits in social behaviour and symptoms. The evidence to date suggests that there may be some specificity of the brain regions involved in these 4 disorders, but all are associated with dysfunction in the amygdala and dorsal cingulate gyrus. Although there is much work remaining in this area, we are beginning to understand the complex interactions of brain function and behaviour that lead to disruptions of social abilities.
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Author information
Author/s: Grady, Cheryl L (CL); Keightley, Michelle L (ML);
Affiliation: Rotman Research Institute, Baycrest Centre for Geriatric Care, Department of Psychology, Department of Psychiatry, University of Toronto, Toronto, Ontario. cgrady@rotman-baycrest.on.ca
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie (Can J Psychiatry), published in Canada. (Language: eng)
Reference: 2002-May; vol 47 (issue 4) : pp 327-36
Dates: Created 2002/05/23; Completed 2002/06/25; Revised 2007/08/01;
PMID: 12025431, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
Comments and Corrections
CommentIn: Can J Psychiatry. 2002 May;47(4):313-4. (PMID: 12025429)
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