 |
| Research article summary (published 29 Jun 2002): |
Social and clinical consequences of cognitive deficits in early psychosis: a two-year follow-up study of first-admitted patients.
Full Abstract
OBJECTIVE:
To explore whether baseline memory and executive deficits predicted poor social and clinical outcome over the 2 years following a first admission for psychosis, regardless of categorical diagnosis.
METHOD:
Cognitive functioning was assessed in first-admitted subjects with psychosis (n=35) with a neuropsychological battery of tests measuring executive, language and memory functions. Social and clinical outcome were assessed at 6-monthly intervals over a two-year follow-up using multiple sources of information.
RESULTS:
A dose-response relationship was found between visual and verbal memory performance at first admission and clinical outcome over the 2-year follow-up:
the poorer the memory performance, the more likely the risk of presenting with psychotic symptoms and rehospitalization. Poor baseline performance on the WCST executive function predicted better medication adherence. No association was found between cognitive performance and occupational or residential outcome.
CONCLUSION:
Cognitive performance was a better predictor of clinical than social outcome in this sample of first-episode patients. The association between cognitive deficits and poor social outcome may be more marked in subjects with chronic psychosis than in first-episode subjects. The finding that cognitive deficits predict better medication adherence is in need of further exploration.
Learn Faster Today Improve your study skills
Author information
Author/s: Verdoux, Hélène (H); Liraud, Florence (F); Assens, François (F); Abalan, François (F); van Os, Jim (J);
Affiliation: Department of Psychiatry, University Victor Segalen Bordeaux 2, Bordeaux, France. helene.verdoux(-atsign-)ipso.u-bordeaux2.fr
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Schizophrenia research (Schizophr Res), published in Netherlands. (Language: eng)
Reference: 2002-Jul; vol 56 (issue 1-2) : pp 149-59
Dates: Created 2002/06/26; Completed 2002/07/31; Revised 2006/11/15;
PMID: 12084429, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article (including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
|
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.