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| Research article summary (published 30 May 2002): |
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Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages.
Full Abstract
Based on research demonstrating associations between folate, B-12 and B-6 vitamins and cognition and mood, we investigated the effects of short-term supplementation in 211 healthy younger, middle-aged and older women who took either 750 microg of folate, 15 microg of vitamin B-12, 75 mg of vitamin B-6 or a placebo daily for 35 d. In addition, we examined associations between dietary intake of these vitamins and cognition and mood. Usual dietary intake status was estimated using a retrospective, self-report, quantified food frequency questionnaire. Participants completed alternate forms of standardized tests of cognitive processing resources, memory, executive function, verbal ability and self-report mood measures before and after supplementation. Supplementation had a significant positive effect on some measures of memory performance only, and no effect on mood. Dietary intake status was associated with speed of processing, recall and recognition and verbal ability.
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Author information
Author/s: Bryan, Janet (J); Calvaresi, Eva (E); Hughes, Donna (D);
Affiliation: Commonwealth Scientific and Industrial Research Organisation, Health Sciences and Nutrition, Kintore Avenue, Adelaide, 5000 Australia.
Journal and publication information
Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal: The Journal of nutrition (J Nutr), published in United States. (Language: eng)
Reference: 2002-Jun; vol 132 (issue 6) : pp 1345-56
Dates: Created 2002/06/03; Completed 2002/06/25; Revised 2006/11/15;
PMID: 12042457, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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