 |
| Research article summary (published 30 Aug 2002): |
Right-sided human prefrontal brain activation during acquisition of conditioned fear.
Full Abstract
This H2(15)O positron emission tomography (PET) study reports on relative regional cerebral blood flow (rCBF) alterations during fear conditioning in humans. In the PET scanner, subjects viewed a TV screen with either visual white noise or snake videotapes displayed alone, then with electric shocks, followed by final presentations of white noise and snakes. Autonomic nervous system responses confirmed fear conditioning only to snakes. To reveal neural activation during acquisition, while equating sensory stimulation, scans during snakes with shocks and white noise alone were contrasted against white noise with shocks and snakes alone. During acquisition, rCBF increased in the right medial frontal gyrus, supporting a role for the prefrontal cortex in fear conditioning to unmasked evolutionary fear-relevant stimuli.
Learn Faster Today Improve your study skills
Author information
Author/s: Fischer, Håkan (H); Andersson, Jesper L R (JL); Furmark, Tomas (T); Wik, Gustav (G); Fredrikson, Mats (M);
Affiliation: Aging Research Center, Karolinska Institute, Stockholm University, Sweden. hakan.fischer@neurotec.ki.se
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Emotion (Washington, D.C.) (Emotion), published in United States. (Language: eng)
Reference: 2002-Sep; vol 2 (issue 3) : pp 233-41
Dates: Created 2003/08/05; Completed 2003/10/27; Revised 2006/11/15;
PMID: 12899356, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article (including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
|
|
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.