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| Research article summary (published 28 Nov 2002): |
Reversed hemispheric asymmetry during simple visual perception in schizophrenia.
Full Abstract
Processing of sensory information in the human brain progresses from primary areas, dedicated to a single sensory feature, to multimodal areas, which integrate many features across sensory modalities. For some of these processes hemispheric dominance has developed. Here we report the results of a passive viewing task using positron emission tomography. Subjects were scanned twice while staring at a stationary visual noise pattern. Normal subjects showed a significant reduction of regional cerebral blood flow (rCBF) in a distributed right hemisphere network of brain regions during the second visual task. Schizophrenic subjects, however, showed significant increases of right hemisphere rCBF during the second visual task and showed significant decreases only in the left hemisphere. These results are consistent with the notion of reversed hemispheric asymmetry during the processing of sensory information in schizophrenia.
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Author information
Author/s: Heckers, Stephan (S); Goff, Donald (D); Weiss, Anthony P (AP);
Affiliation: Department of Psychiatry, Massachusetts General Hospital - East, Harvard Medical School, Charlestown, MA 02129, USA. heckers@psych.mgh.harvard.edu
Journal and publication information
Publication Type: Journal Article
Journal: Psychiatry research (Psychiatry Res), published in Ireland. (Language: eng)
Reference: 2002-Nov; vol 116 (issue 1-2) : pp 25-32
Dates: Created 2002/11/11; Completed 2003/04/17; Revised 2008/04/17;
PMID: 12426031, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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