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| Research article summary (published 27 Feb 2003): |
Psychopathology among persons responding to participation as normal controls in behavioral research studies.
Full Abstract
This study examined the characteristics of persons responding to an advertisement to participate as normal controls in behavioral research studies. Applicants (N = 3,289) inquired by telephone for more information. Of the applicants responding by telephone, 18% met the criteria for a DSM-III-R diagnosis, including psychoactive substance abuse (9%), mood disorder (4%), personality disorder (3%), schizophrenia (1%), anxiety disorder (1%), and neurological disorder (16%). Thirty-two percent (n = 1,045) of individuals passing the telephone interview were evaluated in person. After in-person evaluation, 16% met the criteria for a DSM-III-R diagnosis, including psychoactive substance abuse (9%), mood disorder (3%), personality disorder (3%), schizophrenia (0.1%), anxiety disorder (1%), and neurological disorder (11%). Only 13% (n = 431) of individuals responding by telephone were included as normal controls in ongoing studies. Overall, 79% (n = 2,244) and 57% (n = 590) were excluded by telephone and in-person evaluation, respectively. These results suggest that a high percentage of individuals seeking to participate as normal controls in behavioral research studies have some psychopathology.Copyright 2003, Elsevier Science (USA). All rights reserved.
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Author information
Author/s: Huang, David B (DB); Koo, Hoonmo (H); Dougherty, Don (D); Hassan, Yusuf (Y);
Affiliation: Department of Internal Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Grants: AA-10095 (Agency:United States NIAAA)
Journal and publication information
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
Journal: Comprehensive psychiatry (Compr Psychiatry), published in United States. (Language: eng)
Reference: -2003 Mar-Apr; vol 44 (issue 2) : pp 83-7
Dates: Created 2003/03/26; Completed 2003/07/02; Revised 2007/11/14;
PMID: 12658616, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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