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Research article summary:

Prevention of Alzheimers disease: where we stand.

Abstract Extract:
Alzheimers disease has been recognized as a major public health issue that will grow in prominence as life expectancy increases and as the shape of population demographics shifts toward expansion in the older age ranges with contraction in younger ages. ... (Full abstract text below)

Published 2002Sep in Journal: Curr Neurol Neurosci Rep (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Curr Neurol Neurosci Rep. 2002 Sep;2(5):392-9

Prevention of Alzheimer's disease: where we stand.

Sano M

Department of Neurology, College of Physicians and Surgeons of Columbia University, 630 W. 168th Street, Box 16, New York, NY 10032, USA. ms17@columbia.edu

Alzheimer's disease has been recognized as a major public health issue that will grow in prominence as life expectancy increases and as the shape of population demographics shifts toward expansion in the older age ranges with contraction in younger ages. The magnitude of the problem can be expressed in incidence, prevalence economics, and quality of life. Great strides have been made in understanding and treating this disease, but current clinical management is far from satisfactory and progression seems inevitable once the disease is diagnosed. Such forces in any disease encourage intervention strategies to move from treatment to prevention. However, this vision can only be met with reasonable success when pathology is understood and there is evidence that manipulation of that pathology leads to clinical benefit. This is the challenge that lies ahead to achieve the goal of prevention of Alzheimer's disease. This review begins by examining the progress that has been made in this disease. Current efforts to develop prevention strategies are described and possible agents for future evaluation are discussed.

PMID : 12169218 [PubMed - Indexed for MEDLINE]


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Full Author Information

First NameLastNameInitials
MarySanoM

Affiliation: Department of Neurology, College of Physicians and Surgeons of Columbia University, 630 W. 168th Street, Box 16, New York, NY 10032, USA. ms17@columbia.edu

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This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Category links from this article:

  • Alzheimer Disease - metabolism, physiopathology, therapy
  • Anti-Inflammatory Agents - therapeutic use
  • Cognition - drug effects
  • Estrogen Replacement Therapy
  • Female
  • Ginkgo biloba - drug effects
  • Homocysteine - therapeutic use
  • Humans
  • Lipid Metabolism
  • Male
  • Primary Prevention - methods, trends
   

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