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The placebo effect in alternative medicine: can the performance of a healing ritual have clinical significance?

Full Abstract

In alternative medicine, the main question regarding placebo has been whether a given therapy has more than a placebo effect. Just as mainstream medicine ignores the clinical significance of its own placebo effect, the placebo effect of unconventional medicine is disregarded except for polemics. This essay looks at the placebo effect of alternative medicine as a distinct entity. This is done by reviewing current knowledge about the placebo effect and how it may pertain to alternative medicine. The term placebo effect is taken to mean not only the narrow effect of a dummy intervention but also the broad array of nonspecific effects in the patient-physician relationship, including attention; compassionate care; and the modulation of expectations, anxiety, and self-awareness. Five components of the placebo effect--patient, practitioner, patient-practitioner interaction, nature of the illness, and treatment and setting--are examined. Therapeutic patterns that heighten placebo effects are especially prominent in unconventional healing, and it seems possible that the unique drama of this realm may have "enhanced" placebo effects in particular conditions. Ultimately, only prospective trials directly comparing the placebo effects of unconventional and mainstream medicine can provide reliable evidence to support such claims. Nonetheless, the possibility of enhanced placebo effects raises complex conundrums. Can an alternative ritual with only nonspecific psychosocial effects have more positive health outcomes than a proven, specific conventional treatment? What makes therapy legitimate, positive clinical outcomes or culturally acceptable methods of attainment? Who decides?

 

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Author information

Author/s: Kaptchuk, Ted J (TJ);

Affiliation: Harvard Medical School, Boston, Massachusetts, USA.

Grants: 1R01AT00402-01 (Agency:NCCAM NIH HHS) ; 1R21AT00553 (Agency:NCCAM NIH HHS) ; U24 AR43441 (Agency:NIAMS NIH HHS)

Journal and publication information

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review

Journal: Annals of internal medicine (Ann Intern Med), published in United States. (Language: eng)

Reference: 2002-Jun; vol 136 (issue 11) : pp 817-25

Dates: Created 2002/06/04; Completed 2002/06/19; Revised 2007/11/14;

PMID: 12044130, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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