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Your query 'phase study aithealthy elderly volunteers' matched 882048 abstracts with 1473904 hits. Returning the first 200 results.

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Articles 1 to 10 of 200:

Simvastatin causes changes in affective processes in elderly volunteers.

30 Dec 2005 OBJECTIVES: To test for simvastatin-induced changes in affect and affective processes in elderly volunteers. DESIGN: Randomized, clinical trial. SETTING: The Geriatric Behavioral Psychopharmacology Laboratory at the University of Pennsylvania. ...
rec_pub_16420200-simvastatin-causes-changes-affective-processes-elderly-volunteers.htm

The Von Restorff effect in ageing and Alzheimer's disease.

29 Jun 2006 The purpose of the study was to evaluate the Von Restorff effect in normal ageing and in Alzheimer's disease (AD). A shortened paradigm was administered to three groups of subjects: young volunteers, elderly volunteers and patients with early-stage ...
rec_pub_16897628-the-von-restorff-effect-ageing-alzheimer-s-disease.htm

Hyperpolarized 3He magnetic resonance imaging of ventilation defects in healthy elderly volunteers: initial findings at 3.0 Tesla.

30 May 2008 RATIONALE AND OBJECTIVES: Hyperpolarized (3)He magnetic resonance imaging ventilation defects have been observed in subjects with respiratory disorders. We quantified (3)He ventilation defects in elderly and middle-aged subjects who had no history ...
rec_pub_18486013-hyperpolarized-3he-magnetic-resonance-imaging-ventilation-defects.htm

Effects of multivitamin supplementation on DNA damage in lymphocytes from elderly volunteers.

13 Aug 2007 The aim of this study was to evaluate the effect of a mixture of vitamins and minerals on oxidative DNA damage and the resistance of DNA to H(2)O(2)-induced DNA strand breaks in lymphocytes from 80 elderly volunteers ex vivo by means of Comet ...
rec_pub_17884137-effects-multivitamin-supplementation-dna-damage-lymphocytes-elderly.htm

Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers.

20 Nov 2006 Ampakines act as positive allosteric modulators of AMPA-type glutamate receptors and facilitate hippocampal long-term potentiation (LTP), a mechanism associated with memory storage and consolidation. The present study investigated the acute effects ...
rec_pub_17119538-acute-effects-ampakine-farampator-memory-information-processing.htm

Pharmacokinetics of micafungin in healthy volunteers, volunteers with moderate liver disease, and volunteers with renal dysfunction.

29 Sep 2005 Micafungin is an antifungal agent metabolized by arylsulfatase with secondary metabolism by catechol-O-methyltransferase. The objectives of this study were to estimate the pharmacokinetic parameters and plasma protein binding of micafungin in ...
rec_pub_16172179-pharmacokinetics-micafungin-healthy-volunteers-volunteers-moderate.htm

Plasma ghrelin levels in healthy elderly volunteers: the levels of acylated ghrelin in elderly females correlate positively with serum IGF-I levels and bowel movement frequency and negatively with systolic blood pressure.

30 Jan 2006 Aging is associated with a decrease in growth hormone (GH) secretion, appetite and energy intake. As ghrelin stimulates both GH secretion and appetite, reductions in ghrelin levels may be involved in the reductions in GH secretion and appetite ...
rec_pub_16461559-plasma-ghrelin-levels-healthy-elderly-volunteers-levels-acylated.htm

Effect of methionine loading on pulse wave analysis in elderly volunteers.

30 Jul 2006 OBJECTIVE: To test the hypothesis that an acute increase in plasma homocysteine produced by methionine is associated with an acute increase in pulse wave velocity. DESIGN: A double blind, cross over, placebo controlled design was used and pulse ...
rec_pub_16891444-effect-methionine-loading-pulse-wave-analysis-elderly-volunteers.htm

Alcoholism in the elderly: a study of elderly alcoholics compared with healthy elderly and young alcoholics.

29 Sep 2006 OBJECTIVES: To test the hypothesis that early-onset alcoholism can be differentiated from alcoholism in the elderly by more severe substance related problems, more frequent family history, higher mortality rate, and antisocial behaviour. METHODS: ...
rec_pub_17159815-alcoholism-elderly-study-elderly-alcoholics-compared-healthy-elderly.htm

Lack of significant effects of methionine loading on endothelial function in elderly volunteers.

10 Oct 2006 OBJECTIVE: To test the hypothesis that an acute increase in plasma homocysteine concentration (Hcy) produced by methionine loading is associated with an acute decrease in brachial artery blood flow measured by flow-mediated dilatation (FMD) using ...
rec_pub_17046324-lack-significant-effects-methionine-loading-endothelial-function.htm

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