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Research article summary:

Patterns of change in the treatment of psychiatric symptoms in patients with probable Alzheimers disease from 1983 to 2000.

Abstract Extract:
The authors examined the pattern of use of psychiatric medication as prescribed by community physicians in 1,155 patients with probable Alzheimers disease (AD) referred to the Alzheimers Disease Research Center of Pittsburgh between April 1983 and July ... (Full abstract text below)

Published 2003 in Journal: J Neuropsychiatry Clin Neurosci (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. J Neuropsychiatry Clin Neurosci. 2003 ;15(1):67-73

Patterns of change in the treatment of psychiatric symptoms in patients with probable Alzheimer's disease from 1983 to 2000.

Lopez OL, Becker JT, Sweet RA, Klunk W, Kaufer DI, Saxton J, DeKosky ST

Alzheimer's Disease Research Center, University of Pittsburgh School of Medicine, Pennsylvania, USA. Lopezol@msx.upmc.edu

The authors examined the pattern of use of psychiatric medication as prescribed by community physicians in 1,155 patients with probable Alzheimer's disease (AD) referred to the Alzheimer's Disease Research Center of Pittsburgh between April 1983 and July 2000. The use of antidepressants and of sedatives, hypnotics, and anxiolytics (SHA) increased over time, while the use of antipsychotics decreased. The increased use of antidepressants and decreased use of antipsychotics may reflect the growing evidence that newer antidepressants (e.g., selective serotonin reuptake inhibitors) can be used to treat not only mood-related disorders, but also abnormal behavior (e.g., aggression, agitation) and sleep disorders in AD. Although the use of SHA has a proven deleterious effect on patients with AD, their use has increased over the past two decades.

PMID : 12556574 [PubMed - Indexed for MEDLINE]


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Full Author Information

First NameLastNameInitials
Oscar LLopezOL
James TBeckerJT
Robert ASweetRA
WilliamKlunkW
Daniel IKauferDI
JudithSaxtonJ
Steven TDeKoskyST

Affiliation: Alzheimer's Disease Research Center, University of Pittsburgh School of Medicine, Pennsylvania, USA. Lopezol@msx.upmc.edu

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MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Category links from this article:

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease - diagnosis, drug therapy, psychology
  • Drug Utilization - trends
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Pennsylvania
  • Psychotropic Drugs - administration & dosage, adverse effects
  • Registries
  • Treatment Outcome
   

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