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Research article summary:
Participation of adenosine receptors in neuroprotection.
Abstract Extract:
Adenosine is released from most cells, including neurons and glial cells. Once in the extracellular space, adenosine modifies cell functioning by operating G-protein-coupled receptors. Interaction between adenosine receptors and other receptors for ... (Full abstract text below) Published 2003Mar
in Journal: Drug News Perspect
(Language : eng)
Full Pubmed Extract
This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:
1. Drug News Perspect.
2003 Mar;16(2):80-6
Participation of adenosine receptors in neuroprotection.
Ribeiro JA, Sebastiao AM, de Mendonca A
Neurosciences Laboratory, Faculty of Medicine, University of Lisbon, Portugal. jaribeiro@neurociencias.pt
Adenosine is released from most cells, including neurons and glial cells. Once in the extracellular space, adenosine modifies cell functioning by operating G-protein-coupled receptors. Interaction between adenosine receptors and other receptors for neuromodulators might contribute to a fine tuning of neuronal function, and therefore, to neuroprotection. Manipulation of adenosine receptors may influence sleep and arousal, cognition and memory, neuronal damage and degeneration and neuronal maturation. The therapeutic implications for neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, epilepsy and multiple sclerosis are discussed.
PMID : 12792668 [PubMed - Indexed for MEDLINE]
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Full Author Information
| First Name | LastName | Initials |
| J A | Ribeiro | JA |
| A M | Sebastiao | AM |
| A | de Mendonca | A |
Affiliation: Neurosciences Laboratory, Faculty of Medicine, University of Lisbon, Portugal. jaribeiro@neurociencias.pt
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MESH categories and related page links
This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.
Category links from this article:- Adenosine - physiology
- Drug Design
- Humans
- Mental Processes - physiology
- Nervous System Diseases - metabolism, physiopathology, psychology
- Neurodegenerative Diseases - metabolism, physiopathology, psychology
- Neuronal Plasticity - physiology
- Receptors, Purinergic P1 - physiology
- Synaptic Transmission - physiology
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