Research article summary:

Parallels between cerebellum- and amygdala-dependent conditioning.

Abstract Extract:
Recent evidence from cerebellum-dependent motor learning and amygdala-dependent fear conditioning indicates that, despite being mediated by different brain systems, these forms of learning might use a similar sequence of events to form new memories. In ... (Full abstract text below)

Published 2002Feb in Journal: Nat Rev Neurosci (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Nat Rev Neurosci. 2002 Feb;3(2):122-31

Parallels between cerebellum- and amygdala-dependent conditioning.

Medina JF, Repa JC, Mauk MD, LeDoux JE

Howard Hughes Medical Institute, Department of Physiology, W.M. Keck Foundation Center for Integrative Neurobiology, University of California, 513 Parnassus Avenue, Room HSE-808, San Francisco, California 94143-0444, USA. jmedina@phy.ucsf.edu

Recent evidence from cerebellum-dependent motor learning and amygdala-dependent fear conditioning indicates that, despite being mediated by different brain systems, these forms of learning might use a similar sequence of events to form new memories. In each case, learning seems to induce changes in two different groups of neurons. Changes in the first class of cells are induced very rapidly during the initial stages of learning, whereas changes in the second class of cells develop more slowly and are resistant to extinction. So, anatomically distinct cell populations might contribute differentially to the initial encoding and the long-term storage of memory in these two systems.

PMID : 11836520 [PubMed - Indexed for MEDLINE]

This information is obtained from the National Library of Medicine (NLM). Abstract text and other information may be subject to copyright. Type "NLM copyright" into Google for more information.

Full Author Information

First Name	LastName	Initials
Javier F	Medina	JF
J Christopher	Repa	JC
Michael D	Mauk	MD
Joseph E	LeDoux	JE

Affiliation: Howard Hughes Medical Institute, Department of Physiology, W.M. Keck Foundation Center for Integrative Neurobiology, University of California, 513 Parnassus Avenue, Room HSE-808, San Francisco, California 94143-0444, USA. jmedina@phy.ucsf.edu

3rd Party provider links

Click the links below to go to related 3rd party information:

MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Links for this article

For links to places where you can get the full text of this article see links. Note there may be a subscription or fee required for access to the full text.

New! Using similar technology to this site, we have launched find-health-articles.com, targeting over 1 million health research article abstracts.

Here are some articles related to this one (by title keywords):

Attentional orienting towards smoking-related stimuli.

Preference formation and working memory in Parkinsons disease and normal ageing.

Cerebellar structure and function: making sense of parallel fibers.

Increased amygdala activation to angry and contemptuous faces in generalized social phobia.

The effect of transcranial magnetic stimulation over the cerebellum on the synkinesis of coordinated eye and head movements.

Differential role for the striatum and cerebellum in response to novel movements using a motor learning paradigm.

Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: an fMRI study of autism.

Cerebellar involvement in response reassignment rather than attention.

Audition of laughing and crying leads to right amygdala activation in a low-noise fMRI setting.

Amygdala damage impairs emotion recognition from scenes only when they contain facial expressions.

>>> Get more research article abstracts like these, or browse abstracts.

Keywords in this article:

amygdala, anatomically, brain, case, cells, cerebellum, changes, class, conditioning, contribute, dependent, despite, develop, different, differentially, distinct, encoding, events, evidence, extinction, fear, first, forms, groups, indicates, induce, induced, initial, learning, long, mediated, memories, memory, more, motor, neurons, new, populations, rapidly, recent, resistant, second, seems, sequence, similar, slowly, stages, storage, systems, term, two, whereas

Also, see our new free speed reading online course (beta version)