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Research article summary:

Non-phase locked electroencephalogram (EEG) responses to CO2 laser skin stimulations may reflect central interactions between A partial partial differential- and C-fibre afferent volleys.

Abstract Extract:
OBJECTIVE: By co-activating A partial partial differential- and C-fibre nociceptors, intense CO2 laser heat stimuli produce a dual sensation, composed of first and second pain, but induce only a single A partial partial differential-fibre related late ... (Full abstract text below)

Published 2003Apr in Journal: Clin Neurophysiol (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Clin Neurophysiol. 2003 Apr;114(4):710-22

Non-phase locked electroencephalogram (EEG) responses to CO2 laser skin stimulations may reflect central interactions between A partial partial differential- and C-fibre afferent volleys.

Mouraux A, Guérit JM, Plaghki L

Laboratoire de neurophysiologie (NEFY), Université catholique de Louvain, 54 Avenue Hippocrate, B-1200, Brussels, Belgium. andre.mouraux@nefy.ucl.ac.be <andre.mouraux@nefy.ucl.ac.be>

OBJECTIVE: By co-activating A partial partial differential- and C-fibre nociceptors, intense CO2 laser heat stimuli produce a dual sensation, composed of first and second pain, but induce only a single A partial partial differential-fibre related late laser evoked potential (LEP). However, when avoiding concomitant activation of A partial partial differential-fibres, C-fibre related ultra-late LEPs are recorded. This poorly understood phenomenon was re-investigated using a method which, unlike time-domain averaging, reveals electroencephalogram (EEG) changes whether or not phase-locked to stimulus onset. METHODS: CO2 laser stimuli were applied to the dorsum of the hand. Reaction-time was used to discriminate between A partial partial differential- and C-fibre mediated detections. Analyses were performed using a method based on the time-frequency wavelet transform of EEG epochs. RESULTS: This study revealed: (1) a novel non-phase-locked component related to the activation of A partial partial differential-fibres occurring at similar latencies as the late LEP; and (2) a widespread post-stimulus event-related desynchronization (ERD) induced by both A partial partial differential- and C-fibres.CONCLUSIONS: A partial partial differential- and C-fibre related LEPs could be electrophysiological correlates of similar brain processes, which, when already engaged by A partial partial differential-fibres, cannot or do not need to be reactivated by the later arriving C-fibre afferent volley. A partial partial differential-fibre related ERD could reflect a transient change of state of brain structures generating these responses.

PMID : 12686279 [PubMed - Indexed for MEDLINE]


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Full Author Information

First NameLastNameInitials
AMourauxA
J MGuéritJM
LPlaghkiL

Affiliation: Laboratoire de neurophysiologie (NEFY), Université catholique de Louvain, 54 Avenue Hippocrate, B-1200, Brussels, Belgium. andre.mouraux@nefy.ucl.ac.be <andre.mouraux@nefy.ucl.ac.be>

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MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Category links from this article:

  • Adult
  • Carbon Dioxide
  • Cerebral Cortex - physiology
  • Electroencephalography
  • Evoked Potentials, Somatosensory - physiology
  • Female
  • Humans
  • Lasers
  • Male
  • Middle Aged
  • Models, Neurological
  • Nerve Fibers, Myelinated - physiology
  • Nerve Fibers, Unmyelinated - physiology
  • Perception - physiology
  • Reaction Time - physiology
   

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