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Research article summary:

A new approach to training back-propagation artificial neural networks: empirical evaluation on ten data sets from clinical studies.

Abstract Extract:
We present a new approach to training back-propagation artificial neural nets (BP-ANN) based on regularization and cross-validation and on initialization by a logistic regression (LR) model. The new approach is expected to produce a BP-ANN predictor at ... (Full abstract text below)

Published 2002May in Journal: Stat Med (Language : eng)

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This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Stat Med. 2002 May;21(9):1309-30

A new approach to training back-propagation artificial neural networks: empirical evaluation on ten data sets from clinical studies.

Ciampi A, Zhang F

Department of Epidemiology and Biostatistics, McGill University, 1020 Pine Avenue West, Montreal, P.Q., H3A 1A2 Canada. antonio.ciampi@mcgill.ca

We present a new approach to training back-propagation artificial neural nets (BP-ANN) based on regularization and cross-validation and on initialization by a logistic regression (LR) model. The new approach is expected to produce a BP-ANN predictor at least as good as the LR-based one. We have applied the approach to ten data sets of biomedical interest and systematically compared BP-ANN and LR. In all data sets, taking deviance as criterion, the BP-ANN predictor outperforms the LR predictor used in the initialization, and in six cases the improvement is statistically significant. The other evaluation criteria used (C-index, MSE and error rate) yield variable results, but, on the whole, confirm that, in practical situations of clinical interest, proper training may significantly improve the predictive performance of a BP-ANN.

PMID : 12111880 [PubMed - Indexed for MEDLINE]


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Full Author Information

First NameLastNameInitials
AntonioCiampiA
FulinZhangF

Affiliation: Department of Epidemiology and Biostatistics, McGill University, 1020 Pine Avenue West, Montreal, P.Q., H3A 1A2 Canada. antonio.ciampi@mcgill.ca

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This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Category links from this article:

  • Biometry - methods
  • Clinical Trials as Topic - methods
  • Databases as Topic
  • Female
  • Humans
  • Logistic Models
  • Male
  • Neural Networks (Computer)
  • Predictive Value of Tests
  • Reproducibility of Results
   

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Keywords in this article:

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