Research article summary:

Neuropsychological effects of hyperbaric oxygen therapy in cerebral palsy.

Abstract Extract:
We conducted a double-blind placebo study to investigate the claim that hyperbaric oxygen treatment (HBO2) improves the cognitive status of children with cerebral palsy (CP). Of 111 children diagnosed with CP (aged 4 to 12 years), only 75 were suitable ... (Full abstract text below)

Published 2002Jul in Journal: Dev Med Child Neurol (Language : eng)

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1. Dev Med Child Neurol. 2002 Jul;44(7):436-46

Neuropsychological effects of hyperbaric oxygen therapy in cerebral palsy.

Hardy P, Collet JP, Goldberg J, Ducruet T, Vanasse M, Lambert J, Marois P, Amar M, Montgomery DL, Lecomte JM, Johnston KM, Lassonde M

Groupe de Recherche en Neuropsychologie Expérimentale, Université de Montréal, Québec, Canada.

We conducted a double-blind placebo study to investigate the claim that hyperbaric oxygen treatment (HBO2) improves the cognitive status of children with cerebral palsy (CP). Of 111 children diagnosed with CP (aged 4 to 12 years), only 75 were suitable for neuropsychological testing, assessing attention, working memory, processing speed, and psychosocial functioning. The children received 40 sessions of HBO2 or sham treatment over a 2-month period. Children in the active treatment group were exposed for 1 hour to 100% oxygen at 1.75 atmospheres absolute (ATA), whereas those in the sham group received only air at 1.3 ATA. Children in both groups showed better self-control and significant improvements in auditory attention and visual working memory compared with the baseline. However, no statistical difference was found between the two treatments. Furthermore, the sham group improved significantly on eight dimensions of the Conners' Parent Rating Scale, whereas the active treatment group improved only on one dimension. Most of these positive changes persisted for 3 months. No improvements were observed in either group for verbal span, visual attention, or processing speed.

PMID : 12162381 [PubMed - Indexed for MEDLINE]

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Full Author Information

First Name	LastName	Initials
Paule	Hardy	P
Jean-Paul	Collet	JP
Joanne	Goldberg	J
Thierry	Ducruet	T
Michel	Vanasse	M
Jean	Lambert	J
Pierre	Marois	P
Maxime	Amar	M
David L	Montgomery	DL
Jacqueline M	Lecomte	JM
Karen M	Johnston	KM
Maryse	Lassonde	M

Affiliation: Groupe de Recherche en Neuropsychologie Expérimentale, Université de Montréal, Québec, Canada.

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