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| Research article summary (published 30 May 2002): |
Neuroimaging studies in post-traumatic stress disorder.
Full Abstract
The authors review some of the advances that have been made in understanding the structural, biochemical, and functional neuroanatomy of post-traumatic stress disorder (PTSD). First, the authors review the primary brain regions that had been hypothesized a priori, from the phenomenology and neurobiology of PTSD, to be implicated in the pathophysiology. Next, they review findings from neuroimaging studies of these brain regions in PTSD, and explain the various experimental methods and imaging technologies used in these studies. A broader perspective, including a discussion of additional brain areas that may be involved in PTSD, is synthesized. The authors conclude with a rationale and approach for studies testing sharply defined hypotheses and those using multidisciplinary strategies that integrate neuroimaging data with other cognitive, biologic, and genetic tools to study this complex disorder.
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Author information
Author/s: Grossman, Robert (R); Buchsbaum, Monte S (MS); Yehuda, Rachel (R);
Affiliation: Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. robertgrossman(-atsign-)yahoo.com
Grants: KO8 MH01653-01 (Agency:United States NIMH)
Journal and publication information
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review
Journal: The Psychiatric clinics of North America (Psychiatr Clin North Am), published in United States. (Language: eng)
Reference: 2002-Jun; vol 25 (issue 2) : pp 317-40, vi
Dates: Created 2002/07/24; Completed 2003/01/16; Revised 2007/11/14;
PMID: 12136503, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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