Neurocognitive dimensions characterising patients with first-episode psychosis.

Full Abstract

BACKGROUND:
Assessment of neurocognitive dysfunction in schizophrenia is hampered by the multitude of tests used in the literature.

AIMS:
We aimed to identify the main dimensions of an assessment battery for patients with first-episode psychosis and to estimate the relationship between dimension scores and gender, age, education, diagnosis and symptoms.

METHOD:
Eight frequently used neuropsychological tests were used. We tested 219 patients 3 months after start of therapy or at remission, whichever occurred first.

RESULTS:
We identified five dimensions:
working memory (WM); verbal learning (VL); executive function (EF); impulsivity (im); and motor speed (MS). Significant findings were that the MS score was higher for men, and the WM and VL scores were correlated with years of education.

CONCLUSIONS:
Neurocognitive function in first-episode psychosis is described by at least five independent dimensions.

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Author information

Author/s: Friis, S (S); Sundet, K (K); Rund, B R (BR); Vaglum, P (P); McGlashan, T H (TH);

Affiliation: University of Oslo, Norway. svein.friis(-atsign-)psykiatri.uio.no

Journal and publication information

Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't

Journal: The British journal of psychiatry. Supplement (Br J Psychiatry Suppl), published in England. (Language: eng)

Reference: 2002-Sep; vol 43 (issue ) : pp s85-90

Dates: Created 2002/09/25; Completed 2002/11/22; Revised 2008/02/22;

PMID: 12271806, status: MEDLINE (last retrieval date: 12/26/2008)

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult
Age Factors
Cognition
Education
Female
Humans
Impulsive Behavior - psychology
Male

Memory
Neuropsychological Tests
Psychomotor Performance
Psychotic Disorders - diagnosis; psychology
Schizophrenia - diagnosis
Schizophrenic Psychology
Sex Factors
Verbal Learning

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