Neural systems underlying lexical retrieval for sign language.

Full Abstract

Positron emission tomography was used to investigate whether signed languages exhibit the same neural organization for lexical retrieval within classical and non-classical language areas as has been described for spoken English. Ten deaf native American sign language (ASL) signers were shown pictures of unique entities (famous persons) and non-unique entities (animals) and were asked to name each stimulus with an overt signed response. Proper name signed responses to famous people were fingerspelled, and common noun responses to animals were both fingerspelled and signed with native ASL signs. In general, retrieving ASL signs activated neural sites similar to those activated by hearing subjects retrieving English words. Naming famous persons activated the left temporal pole (TP), whereas naming animals (whether fingerspelled or signed) activated left inferotemporal (IT) cortex. The retrieval of fingerspelled and native signs generally engaged the same cortical regions, but fingerspelled signs in addition activated a premotor region, perhaps due to the increased motor planning and sequencing demanded by fingerspelling. Native signs activated portions of the left supramarginal gyrus (SMG), an area previously implicated in the retrieval of phonological features of ASL signs. Overall, the findings indicate that similar neuroanatomical areas are involved in lexical retrieval for both signs and words.Copyright 2003 Elsevier Science Ltd.

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Author information

Author/s: Emmorey, Karen (K); Grabowski, Thomas (T); McCullough, Stephen (S); Damasio, Hanna (H); Ponto, Laura L B (LL); Hichwa, Richard D (RD); Bellugi, Ursula (U);

Affiliation: Laboratory for Cognitive Neuroscience, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. emmorey(-atsign-)salk.edu

Grants: 1 P50 DC 03189 (Agency:NIDCD NIH HHS)

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal: Neuropsychologia (Neuropsychologia), published in England. (Language: eng)

Reference: 2003-; vol 41 (issue 1) : pp 85-95

Dates: Created 2002/11/12; Completed 2003/03/24; Revised 2007/11/14;

PMID: 12427567, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Male
Memory - physiology
Names
Neurons - physiology
Oxygen - blood
Pattern Recognition, Visual
Semantics
Sign Language
Tomography, Emission-Computed - methods

Associated Chemicals: Oxygen (7782-44-7)

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