Neural correlates of cross-modal binding.

Full Abstract

Little is known about how the brain binds together signals from multiple sensory modalities to produce unified percepts of objects and events in the external world. Using event-related functional magnetic resonance imaging (fMRI) in humans, we measured transient brain responses to auditory/visual binding, as evidenced by a sound-induced change in visual motion perception. Identical auditory and visual stimuli were presented in all trials, but in some trials they were perceived to be bound together and in others they were perceived as unbound unimodal events. Cross-modal binding was associated with higher activity in multimodal areas, but lower activity in predominantly unimodal areas. This activation pattern suggests that a reciprocal and 'competitive' interaction between multimodal and unimodal areas underlies the perceptual interpretation of simultaneous signals from multiple sensory modalities.

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Author information

Author/s: Bushara, Khalafalla O (KO); Hanakawa, Takashi (T); Immisch, Ilka (I); Toma, Keiichiro (K); Kansaku, Kenji (K); Hallett, Mark (M);

Affiliation: Neurology Service, Room 4B135, Minneapolis Veterans Affairs Medical Center, One Veterans Drive, Minneapolis, Minnesota 55417, USA. busha001(-atsign-)umn.edu

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal: Nature neuroscience (Nat Neurosci), published in United States. (Language: eng)

Reference: 2003-Feb; vol 6 (issue 2) : pp 190-5

Dates: Created 2003/01/29; Completed 2003/03/21; Revised 2006/11/15;

PMID: 12496761, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Acoustic Stimulation
Auditory Perception - physiology
Brain - anatomy & histology; physiology
Brain Mapping
Female
Functional Laterality - physiology
Humans
Magnetic Resonance Imaging

Male
Motion Perception - physiology
Nerve Net - anatomy & histology; physiology
Neural Pathways - physiology
Neurons - physiology
Neuropsychological Tests
Photic Stimulation
Psychomotor Performance - physiology

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