Research article summary:

Muscle fractal vascular branching pattern and microvascular perfusion heterogeneity in endurance-trained and untrained men.

Abstract Extract:
Less heterogeneous skeletal muscle perfusion has recently been reported in endurance-trained compared to untrained men at macrovascular level. The causes of this difference in perfusion heterogeneity are unknown as is whether the same difference is ... (Full abstract text below)

Published 2003Jan in Journal: J Physiol (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. J Physiol. 2003 Jan;546(Pt 2):529-35

Muscle fractal vascular branching pattern and microvascular perfusion heterogeneity in endurance-trained and untrained men.

Kalliokoski KK, Kuusela TA, Laaksonen MS, Knuuti J, Nuutila P

Turku PET Centre, University of Turku, FIN-20521 Turku, Finland. kari.kalliokoski@tyks.fi

Less heterogeneous skeletal muscle perfusion has recently been reported in endurance-trained compared to untrained men at macrovascular level. The causes of this difference in perfusion heterogeneity are unknown as is whether the same difference is observed in microvasculature. We hypothesised that the difference could be caused by changes in muscle vascular branching pattern. Perfusion was measured in resting and exercising muscle in 14 endurance-trained and seven untrained men using [(15)O]water and positron emission tomography. Fractal dimension (D) of perfusion distribution was calculated as a measure of fractal characteristics of muscle vascular branching pattern. Perfusion heterogeneity in microvascular units (1 mm(3) samples) was estimated using the measured heterogeneity in voxels of positron emission tomography (PET) images (relative dispersion, RD = S.D./mean) and corresponding D values. D was similar between the groups (exercising muscle 1.11 +/- 0.07 and 1.14 +/- 0.06, resting muscle 1.12 +/- 0.06 and 1.14 +/- 0.03, trained and untrained, respectively). Trained men had lower perfusion (151 +/- 44 vs. 218 +/- 87 ml min(-1) kg(-1), P < 0.05) and macrovascular perfusion heterogeneity (relative dispersion 21 +/- 5 vs. 25 +/- 5 %, P < 0.05) in exercising muscle than untrained men. Furthermore, estimated perfusion heterogeneity in microvascular units in exercising muscle was also lower in trained men (33 +/- 7 vs.48 +/- 19 %, P < 0.05). These results show that fractal vascular branching pattern is similar in endurance-trained and untrained men but perfusion is less heterogeneous at both the macro- and the microvascular level in endurance-trained men. Thus, changes in fractal branching pattern do not explain the differences in perfusion heterogeneity between endurance-trained and untrained men.

PMID : 12527739 [PubMed - Indexed for MEDLINE]

This information is obtained from the National Library of Medicine (NLM). Abstract text and other information may be subject to copyright. Type "NLM copyright" into Google for more information.

Full Author Information

First Name	LastName	Initials
Kari K	Kalliokoski	KK
Tom A	Kuusela	TA
Marko S	Laaksonen	MS
Juhani	Knuuti	J
Pirjo	Nuutila	P

Affiliation: Turku PET Centre, University of Turku, FIN-20521 Turku, Finland. kari.kalliokoski@tyks.fi

3rd Party provider links

Click the links below to go to related 3rd party information:

MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Links for this article

For links to places where you can get the full text of this article see links. Note there may be a subscription or fee required for access to the full text.

New! Using similar technology to this site, we have launched find-health-articles.com, targeting over 1 million health research article abstracts.

Here are some articles related to this one (by title keywords):

Fatigue induced changes in phasic muscle activation patterns for fast elbow flexion movements.

Data and models determine treatment proposals--an illustration from meta-analysis.

Testing stage effects in an ethnically diverse sample.

Are rules applied in Pavlovian electrodermal conditioning with humans general or outcome specific?

Influence of age, sex, and strength training on human muscle gene expression determined by microarray.

The impact of reinforcement density on response differentiation in configural discrimination problems.

Cognitive patterns in subtypes of schizophrenia.

A 10-year experience in nasal reconstruction with the three-stage forehead flap.

Trajectories of brain development: point of vulnerability or window of opportunity?

Robonaut: a robot designed to work with humans in space.

>>> Get more research article abstracts like these, or browse abstracts.

Keywords in this article:

branching, calculated, caused, causes, changes, characteristics, compared, corresponding, difference, differences, dimension, dispersion, distribution, emission, endurance, estimated, exercising, explain, fractal, furthermore, groups, heterogeneity, heterogeneous, hypothesised, images, less, level, lower, macrovascular, mean, measured, men, microvascular, microvasculature, min, muscle, not, observed, pattern, perfusion, pet, positron, rd, recently, relative, reported, respectively, resting, results, same, samples, seven, similar, skeletal, tomography, trained, units, unknown, untrained, values, voxels, vs, water, whether

Also, see our new free speed reading online course (beta version)