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Research article summary:
Multiecho segmented EPI with z-shimmed background gradient compensation (MESBAC) pulse sequence for fMRI.
Abstract Extract:
A MultiEcho Segmented EPI with z-shimmed BAckground gradient Compensation (MESBAC) pulse sequence is proposed and validated for functional MRI (fMRI) study in regions suffering from severe susceptibility artifacts. This sequence provides an effective ... (Full abstract text below) Published 2002Aug
in Journal: Magn Reson Med
(Language : eng)
Full Pubmed Extract
This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:
1. Magn Reson Med.
2002 Aug;48(2):312-21
Multiecho segmented EPI with z-shimmed background gradient compensation (MESBAC) pulse sequence for fMRI.
Li Z, Wu G, Zhao X, Luo F, Li SJ
Biophysics Research Institute, Medical College of Wisconsin, Milwaukee 53226, USA.
A MultiEcho Segmented EPI with z-shimmed BAckground gradient Compensation (MESBAC) pulse sequence is proposed and validated for functional MRI (fMRI) study in regions suffering from severe susceptibility artifacts. This sequence provides an effective tradeoff between spatial and temporal resolution and reduces image distortion and signal dropout. The blood oxygenation level-dependent (BOLD)-weighted fMRI signal can be reliably obtained in the region of the orbitofrontal cortex (OFC). To overcome physiological motion artifacts during prolonged multisegment EPI acquisition, two sets of navigator echoes were acquired in both the readout and phase-encoding directions. Ghost artifacts generally produced by single-shot EPI acquisition were eliminated by separately placing the even and odd echoes in different k-space trajectories. Unlike most z-shim methods that focus on increasing temporal resolution for event-related functional brain mapping, the MESBAC sequence simultaneously addresses problems of image distortion and signal dropout while maintaining sufficient temporal resolution. The MESBAC sequence will be particularly useful for pharmacological and affective fMRI studies in brain regions such as the OFC, nucleus accumbens, amygdala, parahippocampus, etc.
PMID : 12210940 [PubMed - Indexed for MEDLINE]
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Full Author Information
| First Name | LastName | Initials |
| Zhu | Li | Z |
| Gaohong | Wu | G |
| Xiaoli | Zhao | X |
| Feng | Luo | F |
| Shi-Jiang | Li | SJ |
Affiliation: Biophysics Research Institute, Medical College of Wisconsin, Milwaukee 53226, USA.
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Category links from this article:- Adult
- Artifacts
- Brain Mapping
- Cerebral Cortex - physiology
- Cerebrovascular Circulation
- Echo-Planar Imaging - methods
- Humans
- Magnetic Resonance Imaging - methods
- Psychomotor Performance
- Smell - physiology
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