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| Research article summary (published 30 Dec 2001): |
MRI morphometric study and correlation with cognitive functions in young adults shunted for congenital hydrocephalus related to spina bifida.
Full Abstract
We studied the morphometric MRI findings and their correlation with cognitive functions in a population of 10 young adults shunted for congenital hydrocephalus related to spina bifida. Morphometric MRI analysis included measurement of the ventricular dilatation index, frontal and occipital parenchymal thickness and the size of the corpus callosum. The neuropsychological status was evaluated, notably to look for a discrepancy between verbal and performance skills, a finding which has previously been described in hydrocephalic children. We also investigated whether there was a correlation between cognitive function and cerebral morphometric indexes. In each case, MRI demonstrated the structural changes associated with the Chiari II malformation. The size of the lateral ventricles varied, ranging from important dilatation to small ventricles. Six patients had only partial development of the corpus callosum. All patients had a normal global IQ. In our population of young adults, we did not observe any discrepancy between verbal and visuospatial performances as has been described in children with hydrocephalus. We found no relationship between cognitive function and ventricle dilatation or parenchymal thickness or between the size of the corpus callosum and callosal transfer.Copyright 2002 S. Karger AG, Basel
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Author information
Author/s: Hommet, C (C); Cottier, J P (JP); Billard, C (C); Perrier, D (D); Gillet, P (P); De Toffol, B (B); Sirinelli, D (D); Bertrand, P (P); Autret, A (A);
Affiliation: Service de Neurologie, Hôpital Bretonneau, Tours, France. hommet(-atsign-)med.univ-tours.fr
Journal and publication information
Publication Type: Journal Article
Journal: European neurology (Eur Neurol), published in Switzerland. (Language: eng)
Reference: 2002-; vol 47 (issue 3) : pp 169-74
Dates: Created 2002/03/26; Completed 2002/06/07; Revised 2004/11/17;
PMID: 11914556, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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