 |
| Research article summary (published 30 May 2003): |
Motor-related functional subdivisions of human lateral premotor cortex: epicortical recording in conditional visuomotor task.
Full Abstract
OBJECTIVE:
To clarify the functional subdivisions of the human lateral premotor cortex (PM) in the visuomotor control.
METHODS:
Event-related potentials (ERPs) were epicortically recorded from PM in 5 epilepsy patients. S1-Go/NoGo choice delayed reaction time (RT), S1-warned S2-Go simple RT and control fixation paradigms were compared using paired visual stimuli (S1, S2).
RESULTS:
Signal-related activity peaked at 176-194 ms after S1 in the ventrorostral PM (PMvr) in all 3 paradigms, indicating its role in signal perception. Early set-related activity was recorded with its peak <810 ms after S1 in the dorsorostral PM (PMdr) and was larger in the choice than in the simple RT paradigm, suggesting its role in signal selection. Its cognitive component was recorded as surface-positive transients at PMdr, while its motoric aspect, seen as negative transients, extended to the caudal PM. Late sustained set-related activity was observed in preparation for hand movement in the caudal PM at the hand and face positive motor areas. After presentation of S2, movement-related activity was observed at the hand sensorimotor area for motor execution, following the signal-related activity at PMvr.
CONCLUSIONS:
The present ERP study suggests the temporally sequential representation of predominantly 'cognitive' function in the rostral PM and 'motor' function in the caudal PM.
SIGNIFICANCE:
The rostrocaudal cognitive-motor gradient was demonstrated in the lateral premotor cortex in humans by means of an epicortical ERP approach.
Learn Faster Today Improve your study skills
Author information
Author/s: Matsumoto, Riki (R); Ikeda, Akio (A); Ohara, Shinji (S); Matsuhashi, Masao (M); Baba, Kouichi (K); Yamane, Fumitaka (F); Hori, Tomokatsu (T); Mihara, Tadahiro (T); Nagamine, Takashi (T); Shibasaki, Hiroshi (H);
Affiliation: Human Brain Research Center, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, 606-8507, Kyoto, Japan
Journal and publication information
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology (Clin Neurophysiol), published in Netherlands. (Language: eng)
Reference: 2003-Jun; vol 114 (issue 6) : pp 1102-15
Dates: Created 2003/06/13; Completed 2003/08/01; Revised 2008/09/10;
PMID: 12804679, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article (including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
|
|
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.