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| Research article summary (published 29 Nov 2002): |
Motor and phosphene thresholds to transcranial magnetic stimuli: a reproducibility study.
Full Abstract
OBJECTIVES:
As repetitive transcranial magnetic stimulation (rTMS) is often applied on different days, it is of interest to know whether motor (MT) and phosphene (PT) thresholds are reproducible across time and whether the intensity determined on the first day can be used in subsequent sessions.
METHODS:
We studied MT and PT over 5 separate recordings in 10 healthy volunteers using a focal coil and a Magstim(Rapid stimulator. After the initial recording (session 1), the others (2 to 5) were performed respectively after 1 day, 7 days, 1 month and 4 months.
RESULTS:
Mean MT at rest were 65.30 +/- 5.54%, 65.7 +/- 7.18%, 60.4 +/- 4.27%, 61.8 +/- 4.34%, and 63 +/- 9.1% at sessions 1 to 5. Mean PT were 71.43 +/- 6.68%, 66.29 +/- 10.67%, 60.71 +/- 8.64%, 60.57 +/- 8.08%, and 68.71 +/- 15.48% at sessions 1 to 5. MT and PT were reproducible (ANOVA analysis), however, as shown by coefficients of variation, variability between the first 3 sessions exceeded 10% for MT in 3 subjects and in 4 subjects for PT.
CONCLUSIONS:
It seems preferable to determine thresholds and adapt output intensity of the stimulator at each rTMS session.
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Author information
Author/s: Fumal, A (A); Bohotin, V (V); Vandenheede, M (M); Seidel, L (L); Maertens de Noordhout, A (A); Schoenen, J (J);
Affiliation: Departments of Neurology, Neuroanatomy, University of Liège, B-4000 Liège, Belgium.
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: Acta neurologica Belgica (Acta Neurol Belg), published in Belgium. (Language: eng)
Reference: 2002-Dec; vol 102 (issue 4) : pp 171-5
Dates: Created 2003/01/21; Completed 2003/03/21; Revised 2006/11/15;
PMID: 12534244, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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