Research article summary:

Maturation of human central auditory system activity: the T-complex.

Abstract Extract:
OBJECTIVE: The purpose of this study was to evaluate and describe the maturation of a set of auditory evoked potentials (AEPs) described as the T-complex from a large group of children, adolescents, and young adults who ranged in age from 5 to 20 years ... (Full abstract text below)

Published 2003Apr in Journal: Clin Neurophysiol (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Clin Neurophysiol. 2003 Apr;114(4):685-701

Maturation of human central auditory system activity: the T-complex.

Tonnquist-Uhlen I, Ponton CW, Eggermont JJ, Kwong B, Don M

Department of Audiology, Karolinska Hospital, Stockholm, Sweden.

OBJECTIVE: The purpose of this study was to evaluate and describe the maturation of a set of auditory evoked potentials (AEPs) described as the T-complex from a large group of children, adolescents, and young adults who ranged in age from 5 to 20 years of age. METHODS: The AEPs evoked by brief trains of clicks presented to the left ear were measured at 30 scalp-electrode locations. Analyses focused on age-related latency and amplitude changes in the T-complex recorded at the temporal electrode sites T3 and T5 over the left hemisphere and T4 and T6 over the right hemisphere. The maturation of the T-complex components Na, Ta, and Tb was contrasted with those of the obligatory AEPs P1, N1b, and P2 measured at electrodes C3 and C4. RESULTS: T-complex activity was present in the grand average AEPs of all 14 age groups spanning ages 5-20 years. T-complex components recorded at electrodes T3 and T4 differed in both morphology and maturation rate from those recorded at T5 and T6. In contrast to the prolonged maturation of AEP latency measured at electrodes T5 and T6, the T-complex components measured at electrodes T3 and T4 did not show a significant overall change in peak latency as a function of age. Consistent amplitude and latency correlations were found between the obligatory AEP components P1, N1b and P2 recorded at C3 and C4 and the T-complex components measured at T5 and T6, but not T3 and T4. CONCLUSIONS: Distinct patterns of AEP maturation were measured at electrode sites commonly used to record the T-complex. At scalp electrodes located over more posterior temporal areas (T5 and T6), the AEPs were characterized by a prolonged pattern of maturation very similar to that measured at the central electrodes C3 and C4. These findings and others reported in this paper provide strong evidence that the AEPs recorded at electrodes T5 and T6 are not T-complex peaks. In contrast, the AEPs measured at electrodes T3 and T4 over more anterior temporal scalp areas appear largely independent of activity measured at the central electrode locations. The T-complex peaks Ta and Tb measured at these scalp locations mature early, with no overall significant age-related changes in peak latencies. SIGNIFICANCE: The T-complex is recorded from the temporal electrodes T3 and T4 represents activity of secondary auditory cortex better than, and independent from, midline potentials. Its robust presence in 5-8 year olds supports its potential usefulness in assessing language impairment.

PMID : 12686277 [PubMed - Indexed for MEDLINE]

This information is obtained from the National Library of Medicine (NLM). Abstract text and other information may be subject to copyright. Type "NLM copyright" into Google for more information.

Full Author Information

First Name	LastName	Initials
Inger	Tonnquist-Uhlen	I
Curtis W	Ponton	CW
Jos J	Eggermont	JJ
Betty	Kwong	B
Manuel	Don	M

Affiliation: Department of Audiology, Karolinska Hospital, Stockholm, Sweden.

3rd Party provider links

Click the links below to go to related 3rd party information:

MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Links for this article

For links to places where you can get the full text of this article see links. Note there may be a subscription or fee required for access to the full text.

New! Using similar technology to this site, we have launched find-health-articles.com, targeting over 1 million health research article abstracts.

Here are some articles related to this one (by title keywords):

Expression of BRG1, a human SWI/SNF component, affects the organisation of actin filaments through the RhoA signalling pathway.

Perceptual weights in auditory level discrimination.

Perceptual learning of temporal structure.

Limitations on rate discrimination.

Intervocalic consonants in the acquisition of German: onsets, codas or something else?

Inhibition of expected movements in Tourettes Syndrome.

Disturbed monitoring and response inhibition in patients with Gilles de la Tourette syndrome and co-morbid obsessive compulsive disorder.

Abnormal line bisection judgements in children with Tourettes syndrome.

Finger interactions studied with transcranial magnetic stimulation during multi-finger force production tasks.

Embodied experience and linguistic meaning.

>>> Get more research article abstracts like these, or browse abstracts.

Keywords in this article:

activity, adolescents, adults, aeps, age, ages, amplitude, analyses, anterior, appear, areas, assessing, auditory, average, better, brief, central, changes, characterized, children, clicks, commonly, complex, components, conclusions, consistent, contrasted, correlations, cortex, describe, described, differed, distinct, early, electrode, electrodes, evaluate, evidence, evoked, findings, focused, function, grand, group, groups, hemisphere, independent, language, large, largely, latencies, latency, left, located, locations, maturation, mature, measured, methods, midline, more, morphology, not, objective, obligatory, olds, others, over, paper, patterns, peak, peaks, posterior, potentials, presence, presented, prolonged, provide, purpose, ranged, rate, recorded, related, reported, represents, results, right, robust, scalp, secondary, set, significance, significant, similar, sites, spanning, strong, study, supports, ta, tb, temporal, trains, usefulness, who, years, young

Also, see our new free speed reading online course (beta version)