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Research article summary:

The longitudinal axis of the hippocampal formation: its anatomy, circuitry, and role in cognitive function.

Abstract Extract:
The ability to learn and access new memories requires an intact hippocampal formation, a complex three-dimensional structure that spans the anterior-posterior aspect of the temporal lobe. Historically, the transverse axis has dominated studies exploring ... (Full abstract text below)

Published 2002 in Journal: Rev Neurosci (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. Rev Neurosci. 2002 ;13(2):183-94

The longitudinal axis of the hippocampal formation: its anatomy, circuitry, and role in cognitive function.

Small SA

The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, The Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA. sas68@columbia.edu

The ability to learn and access new memories requires an intact hippocampal formation, a complex three-dimensional structure that spans the anterior-posterior aspect of the temporal lobe. Historically, the transverse axis has dominated studies exploring mnemonic properties of the hippocampus, but in the last decade the importance of the long axis has been coming into focus. Anatomical and physiological findings are reviewed suggesting that the long axis functions as a circuit. Recent imaging studies investigating the long axis as a circuit are summarized, pointing to specific mechanisms that can account for how the hippocampus associates separate sensory input during memory acquisition and recall.

PMID : 12160261 [PubMed - Indexed for MEDLINE]


This information is obtained from the National Library of Medicine (NLM). Abstract text and other information may be subject to copyright. Type "NLM copyright" into Google for more information.

Full Author Information

First NameLastNameInitials
Scott ASmallSA

Affiliation: The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, The Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA. sas68@columbia.edu

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Category links from this article:

  • Animals
  • Cognition - physiology
  • Hippocampus - anatomy & histology, physiology
  • Humans
  • Magnetic Resonance Imaging
  • Models, Anatomic
  • Nerve Net
   

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