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Research article summary:
Lexical decision of nonwords and pseudowords in humans: a positron emission tomography study.
Abstract Extract: In this functional positron emission tomography study brain activations during an auditory lexical decision task with two experimental conditions were investigated. First, the subjects had to discriminate between real words and nonwords; second, real ... (Full abstract text below) Published 2003Jul
in Journal: Neurosci Lett
(Language : eng)
Full Pubmed Extract
This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:
1. Neurosci Lett.
2003 Jul;345(3):177-81
Lexical decision of nonwords and pseudowords in humans: a positron emission tomography study.
Specht K, Holtel C, Zahn R, Herzog H, Krause BJ, Mottaghy FM, Radermacher I, Schmidt D, Tellmann L, Weis S, Willmes K, Huber W
Division of Neurolinguistics, Neurology Department, University Hospital Aachen, Aachen, Germany. specht@mcbonn.de
In this functional positron emission tomography study brain activations during an auditory lexical decision task with two experimental conditions were investigated. First, the subjects had to discriminate between real words and nonwords; second, real words varied with pseudowords. Comparing each of these tasks to an auditory control condition we found bilateral activation of the superior temporal and inferior frontal gyrus, lateralized to the left in the pseudoword condition. The comparison of the lexical decision tasks revealed higher rCBF during the pseudo-/real word decisions within BA 47, adjacent to Broca's area, and the anterior cingulate. The data support the notion that the lexical decision during a nonword task is mainly based on a phonological discrimination process, whereas a pseudoword task more strongly requires lexical access resulting in activation of BA 47.
PMID : 12842285 [PubMed - Indexed for MEDLINE]
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Full Author Information
| First Name | LastName | Initials |
| Karsten | Specht | K |
| Chrisitane | Holtel | C |
| Roland | Zahn | R |
| Hans | Herzog | H |
| Bernd J | Krause | BJ |
| Felix M | Mottaghy | FM |
| Irmgard | Radermacher | I |
| Daniela | Schmidt | D |
| Lutz | Tellmann | L |
| Susanne | Weis | S |
| Klaus | Willmes | K |
| Walter | Huber | W |
Affiliation: Division of Neurolinguistics, Neurology Department, University Hospital Aachen, Aachen, Germany. specht@mcbonn.de
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MESH categories and related page links
This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.
Category links from this article:- Acoustic Stimulation
- Adult
- Auditory Perception
- Brain - anatomy & histology, physiology
- Brain Mapping
- Discrimination (Psychology) - physiology
- Humans
- Language
- Male
- Phonetics
- Semantics
- Tomography, Emission-Computed
- Verbal Behavior - physiology
- Verbal Learning
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