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Research article summary:
Involvement of the human cerebellum in fear-conditioned potentiation of the acoustic startle response: a PET study.
Abstract Extract:
Fear-conditioned potentiation of the startle response was used to study the role of the cerebellum in associative learning of non-specific aversive reactions in healthy human subjects using PET. Prior PET scanning initially neutral light stimuli were ... (Full abstract text below) Published 2002Jul
in Journal: Neuroreport
(Language : eng)
Full Pubmed Extract
This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:
1. Neuroreport.
2002 Jul;13(10):1275-8
Involvement of the human cerebellum in fear-conditioned potentiation of the acoustic startle response: a PET study.
Frings M, Maschke M, Erichsen M, Jentzen W, Müller SP, Kolb FP, Diener HC, Timmann D
Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Fear-conditioned potentiation of the startle response was used to study the role of the cerebellum in associative learning of non-specific aversive reactions in healthy human subjects using PET. Prior PET scanning initially neutral light stimuli were paired with painful electric shocks (fear-conditioning phase). Four PET-scans each were performed with presentation of acoustic startle stimuli (T), fear-conditioned light stimuli (L) or acoustic stimuli paired with light (LT, potentation phase). As a measure of fear-conditioning subtraction of condition T from LT revealed an increase of regional cerebellar blood flow (rCBF) in the left cerebellar hemisphere. Subtraction of condition L from LT, as a measure of fear-conditioned potentiation, revealed an increase of rCBF in the medial cerebellum. Different parts of the cerebellum appear to be involved in this form of motor associative learning.
PMID : 12151786 [PubMed - Indexed for MEDLINE]
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Full Author Information
| First Name | LastName | Initials |
| Markus | Frings | M |
| Matthias | Maschke | M |
| Maren | Erichsen | M |
| Walter | Jentzen | W |
| Stefan P | Müller | SP |
| Florian P | Kolb | FP |
| Hans-Christoph | Diener | HC |
| Dagmar | Timmann | D |
Affiliation: Department of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany.
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MESH categories and related page links
This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.
Category links from this article:- Acoustic Stimulation
- Adult
- Association Learning - physiology
- Cerebellum - blood supply, physiology
- Conditioning (Psychology) - physiology
- Fear - physiology
- Humans
- Male
- Startle Reaction - physiology
- Tomography, Emission-Computed
| | Related Memletics topics: |
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