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| Research article summary (published 30 Jan 2003): |
Intracortical inhibition and facilitation in paired-pulse transcranial magnetic stimulation: effect of conditioning stimulus intensity on sizes and latencies of motor evoked potentials.
Full Abstract
The influence of the intensity of the conditioning stimulus on intracortical inhibition (ICI) and intracortical facilitation (ICF) was assessed in a study using paired-pulse transcranial magnetic stimulation. Interstimulus intervals (ISIs) between conditioning and test stimuli were 3 msec and 13 msec. Latencies and areas of motor evoked potentials in response to the test stimulus were measured in the right extensor carpi radialis muscle. Motor evoked potential areas with ISIs of 3 msec and 13 msec showed a different dependence on the intensity of the conditioning stimulus. In contrast, the changes of motor evoked potential latencies were fairly similar with both ISIs. The findings point to a parallel action of ICI and ICF. Furthermore, the latencies seem to be a more sensitive indicator for ICF action than the size parameters of motor evoked potentials.
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Author information
Author/s: Kossev, Andon R (AR); Siggelkow, Sabine (S); Dengler, Reinhard (R); Rollnik, Jens D (JD);
Affiliation: Institute of Biophysics, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Journal and publication information
Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal: Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society (J Clin Neurophysiol), published in United States. (Language: eng)
Reference: 2003-Feb; vol 20 (issue 1) : pp 54-8
Dates: Created 2003/04/09; Completed 2003/05/21; Revised 2006/11/15;
PMID: 12684559, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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