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| Research article summary (published 30 Aug 2002): |
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Gustatory evoked cortical activity in humans studied by simultaneous EEG and MEG recording.
Full Abstract
Evoked potentials are widely used in clinical medicine for objective evaluation of sensory disturbances. However, gustatory evoked potentials (GEPs) have not been extensively studied due to lack of agreement among investigators regarding the waveforms. In this study GEPs and gustatory magnetic fields (GEMfs) were simultaneously recorded from five subjects in response to 0.3 M NaCl in an attempt to establish GEP recording as an objective gustatometer. Each subject received a total of 240 stimulus presentations over six sessions. Three GEP components (P1, N1 and P2) were observed and correlated with their corresponding equivalent current dipoles (ECD1, ECD2 and ECD3, respectively). ECD1 was localized to area G in all subjects, P1 being the indicator of intact gustatory projection to area G. No significant GEP activity was detected during the time preceding P1, which suggests that there was no activity in cortical gyri other than that detected by magnetoencephalography. ECD2 and ECD3 were localized to various cortical structures, including the inferior insula and the superior temporal sulcus, indicating that N1 and P2 reflect higher order gustatory functions. The present results indicate that measurement of GEPs may be useful for objective evaluation of gustatory disturbance.
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Author information
Author/s: Mizoguchi, Chie (C); Kobayakawa, Tatsu (T); Saito, Sachiko (S); Ogawa, Hisashi (H);
Affiliation: Human Perception and Cognition Group, Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Higashi 1-1, Tsukuba 305-8566, Japan.
Journal and publication information
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal: Chemical senses (Chem Senses), published in England. (Language: eng)
Reference: 2002-Sep; vol 27 (issue 7) : pp 629-34
Dates: Created 2002/08/29; Completed 2003/03/07; Revised 2006/11/15;
PMID: 12200343, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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