 |
| Research article summary (published 31 Mar 2003): |
Frontotemporal dementia.
Full Abstract
In this case study, we describe the symptoms, neuropsychological testing, and brain pathology of a man with frontotemporal dementia (FTD). FTD most often presents with either a change in personality or behavior, such as social withdrawal, increased gregariousness, disinhibition, or obsessive behaviors; or with impairment of language function. Memory difficulties are common, but usually are less prominent than these other symptoms in the early stages of the disease. Frequently, psychiatric diagnoses are initially the primary consideration. Cases may be either familial or sporadic. In this familial case, an autopsy was ultimately performed and revealed findings characteristic of FTD, with grossly evident focal brain degeneration in the frontal and temporal regions, microscopic signs of gliosis, and cellular abnormalities of the intracellular microtubule-associated protein tau.
Learn Faster Today Improve your study skills
Author information
Author/s: Honig, Lawrence S (LS); Bell, Karen (K); Chin, Steven S (SS);
Affiliation: Columbia University College of Physicians and Surgeons, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Gertrude H. Sergievsky Center, and the Department of Neurology, New York, NY 10032, USA. lh456(-atsign-)columbia.edu
Journal and publication information
Publication Type: Case Reports; Journal Article
Journal: Science of aging knowledge environment : SAGE KE (Sci Aging Knowledge Environ), published in United States. (Language: eng)
Reference: 2003-Apr; vol 2003 (issue 13) : pp DN1
Dates: Created 2003/07/07; Completed 2003/09/04; Revised 2004/11/17;
PMID: 12844524, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
External Links for this article (including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
|
|
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.