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Research article summary:
Exogenous and endogenous components of ultralate (C-fibre) evoked potentials following CO2 laser stimuli to tiny skin surface areas in healthy subjects.
Abstract Extract: CO2 laser stimulation of tiny skin surface areas on the hand dorsum generate ultralate laser evoked potentials (LEPs) with a major positivity maximal at the vertex at a latency of about 1 s. These potentials follow selective and direct activation of ... (Full abstract text below) Published 2003Apr
in Journal: Neurophysiol Clin
(Language : eng)
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This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:
1. Neurophysiol Clin.
2003 Apr;33(2):78-85
Exogenous and endogenous components of ultralate (C-fibre) evoked potentials following CO2 laser stimuli to tiny skin surface areas in healthy subjects.
Opsommer E, Guérit JM, Plaghki L
Faculty of Medicine, Université catholique de Louvain, Avenue Mounier 53/READ 5375, B-1200, Brussels, Belgium. opsommer@read.ucl.ac.be <opsommer@read.ucl.ac.be>
CO2 laser stimulation of tiny skin surface areas on the hand dorsum generate ultralate laser evoked potentials (LEPs) with a major positivity maximal at the vertex at a latency of about 1 s. These potentials follow selective and direct activation of C-fibres in the superficial layers of the skin. To identify the endogenous P3 component in ultralate LEPs, we used a 2-stimulus oddball paradigm (20% probability of targets). Ultralate LEPs were recorded in eight healthy subjects with 19 channels EEG and EOG. Laser stimuli (n = 200/subject, < 0.5 mm diameter, 5 ms duration, 9.4 mJ/mm2 energy density) were applied in a pseudo-random order to the proximal phalanx of either middle finger (target) or index (non-target) of the left hand. Vigilance was maintained during recording sessions. Subject's task was to press a button to any kind of sensation perceived at the target zone. We observed a negative-positive (N965-P1139) complex maximal at Cz for all stimulus conditions. This complex was of significantly larger amplitude for rare events. For the target responses, a second distinct positive peak was observed with a mean latency of 1343 +/- 103.5 ms with maximum amplitude at Pz. This latest peak may represent an endogenous P3-like component as it is linked to the subject's detection of the target stimulus (rare events).
PMID : 12837575 [PubMed - Indexed for MEDLINE]
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Full Author Information
| First Name | LastName | Initials |
| Emmanuelle | Opsommer | E |
| Jean-Michel | Guérit | JM |
| Léon | Plaghki | L |
Affiliation: Faculty of Medicine, Université catholique de Louvain, Avenue Mounier 53/READ 5375, B-1200, Brussels, Belgium. opsommer@read.ucl.ac.be <opsommer@read.ucl.ac.be>
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This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.
Category links from this article:- Adult
- Electroencephalography
- Electrooculography
- Evoked Potentials - physiology
- Female
- Humans
- Lasers
- Male
- Nerve Fibers, Unmyelinated - physiology
- Photic Stimulation
- Reaction Time - physiology
- Skin - innervation
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