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Research article summary:

Exogenous and endogenous components of ultralate (C-fibre) evoked potentials following CO2 laser stimuli to tiny skin surface areas in healthy subjects.

Abstract Extract:
CO2 laser stimulation of tiny skin surface areas on the hand dorsum generate ultralate laser evoked potentials (LEPs) with a major positivity maximal at the vertex at a latency of about 1 s. These potentials follow selective and direct activation of ... (Full abstract text below)

Published 2003Apr in Journal: Neurophysiol Clin (Language : eng)

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1. Neurophysiol Clin. 2003 Apr;33(2):78-85

Exogenous and endogenous components of ultralate (C-fibre) evoked potentials following CO2 laser stimuli to tiny skin surface areas in healthy subjects.

Opsommer E, Guérit JM, Plaghki L

Faculty of Medicine, Université catholique de Louvain, Avenue Mounier 53/READ 5375, B-1200, Brussels, Belgium. opsommer@read.ucl.ac.be <opsommer@read.ucl.ac.be>

CO2 laser stimulation of tiny skin surface areas on the hand dorsum generate ultralate laser evoked potentials (LEPs) with a major positivity maximal at the vertex at a latency of about 1 s. These potentials follow selective and direct activation of C-fibres in the superficial layers of the skin. To identify the endogenous P3 component in ultralate LEPs, we used a 2-stimulus oddball paradigm (20% probability of targets). Ultralate LEPs were recorded in eight healthy subjects with 19 channels EEG and EOG. Laser stimuli (n = 200/subject, < 0.5 mm diameter, 5 ms duration, 9.4 mJ/mm2 energy density) were applied in a pseudo-random order to the proximal phalanx of either middle finger (target) or index (non-target) of the left hand. Vigilance was maintained during recording sessions. Subject's task was to press a button to any kind of sensation perceived at the target zone. We observed a negative-positive (N965-P1139) complex maximal at Cz for all stimulus conditions. This complex was of significantly larger amplitude for rare events. For the target responses, a second distinct positive peak was observed with a mean latency of 1343 +/- 103.5 ms with maximum amplitude at Pz. This latest peak may represent an endogenous P3-like component as it is linked to the subject's detection of the target stimulus (rare events).

PMID : 12837575 [PubMed - Indexed for MEDLINE]


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Full Author Information

First NameLastNameInitials
EmmanuelleOpsommerE
Jean-MichelGuéritJM
LéonPlaghkiL

Affiliation: Faculty of Medicine, Université catholique de Louvain, Avenue Mounier 53/READ 5375, B-1200, Brussels, Belgium. opsommer@read.ucl.ac.be <opsommer@read.ucl.ac.be>

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Category links from this article:

  • Adult
  • Electroencephalography
  • Electrooculography
  • Evoked Potentials - physiology
  • Female
  • Humans
  • Lasers
  • Male
  • Nerve Fibers, Unmyelinated - physiology
  • Photic Stimulation
  • Reaction Time - physiology
  • Skin - innervation
   

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