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| Research article summary (published 30 May 2003): |
Ethical aspects of living donor kidney transplantation and recipient adherence to treatment.
Full Abstract
Living donor kidney transplantation comprises approximately 30% of kidney transplantations in the United States and is an effective form of renal replacement therapy, with low risk to the donor. Twenty percent of living donors do not have a genetic relationship with their recipients. In the selection of living donors, guiding ethical principles include altruism, the absence of coercion or monetary reward, patient autonomy, beneficence, and nonmaleficence. In order for the benefit of living donor kidney transplantation to outweigh the risk, evidence that the proposed recipient will care for the transplanted organ must exist. Nonadherence to treatment has been identified as a major risk factor for graft rejection. When nonadherence to treatment regimens leads to loss of the graft, the consequences are felt by the recipient, donor, and the treatment team. The decision to transplant an organ to a noncompliant patient from a cadaveric or a living donor raises issues of patient autonomy, justice, paternalism, and benevolence versus nonmaleficence.
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Author information
Author/s: Wright, Linda (L); Daar, A S (AS);
Affiliation: University Health Network, Toronto, Ontario.
Journal and publication information
Publication Type: Case Reports; Journal Article; Review
Journal: Progress in transplantation (Aliso Viejo, Calif.) (Prog Transplant), published in United States. (Language: eng)
Reference: 2003-Jun; vol 13 (issue 2) : pp 105-9
Dates: Created 2003/07/04; Completed 2003/07/23; Revised 2005/11/16;
PMID: 12841516, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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