Research article summary (published 29 Jun 2002):

Estimating the delay of the fMRI response.

Full Abstract

We propose a fast, efficient, general, simple, valid, and robust method of estimating and making inference about the delay of the fMRI response modeled as a temporal shift of the hemodynamic response function (HRF). We estimate the shift unbiasedly using two optimally chosen basis functions for a spectrum of time shifted HRFs. This is done at every voxel, to create an image of estimated delays and their standard deviations. This can be used to compare delays for the same stimulus at different voxels, or for different stimuli at the same voxel. Our method is compared to other alternatives and validated on an fMRI data set from an experiment in pain perception.

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Author information

Author/s: Liao, C H (CH); Worsley, K J (KJ); Poline, J-B (JB); Aston, J A D (JA); Duncan, G H (GH); Evans, A C (AC);

Affiliation: Department of Mathematics and Statistics, McGill University, Canada.

Journal and publication information

Publication Type: Journal Article

Journal: NeuroImage (Neuroimage), published in United States. (Language: eng)

Reference: 2002-Jul; vol 16 (issue 3 Pt 1) : pp 593-606

Dates: Created 2002/08/09; Completed 2002/09/11; Revised 2007/11/15;

PMID: 12169246, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Brain - blood supply; physiology Cerebrovascular Circulation - physiology Computer Simulation Forearm - innervation Hemodynamics - physiology

Humans Magnetic Resonance Imaging - methods Models, Neurological Reaction Time Reproducibility of Results

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