Research article summary:

Epilepsy presenting as AD: neuroimaging, electroclinical features, and response to treatment.

Abstract Extract:
Three patients with progressive memory impairment initially attributed to AD underwent serial neuropsychometry, MRI, and EEG. Registered serial MRI volumetric analysis showed no loss of whole or regional brain volume. EEG revealed temporal lobe spike ... (Full abstract text below)

Published 2002Jan in Journal: Neurology (Language : eng)

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1. Neurology. 2002 Jan;58(2):298-301

Epilepsy presenting as AD: neuroimaging, electroclinical features, and response to treatment.

Høgh P, Smith SJ, Scahill RI, Chan D, Harvey RJ, Fox NC, Rossor MN

Dementia Research Group, Department of Clinical Neurology, Institute of Neurology, Queen Square, London, UK.

Three patients with progressive memory impairment initially attributed to AD underwent serial neuropsychometry, MRI, and EEG. Registered serial MRI volumetric analysis showed no loss of whole or regional brain volume. EEG revealed temporal lobe spike activity and antiepileptic treatment was optimized. Memory functions improved with antiepileptic medication in all three patients. The demonstration of temporal lobe spike activity in patients with progressive memory impairment is an indication for a trial of antiepileptic medication.

PMID : 11805262 [PubMed - Indexed for MEDLINE]

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Full Author Information

First Name	LastName	Initials
P	Høgh	P
S J	Smith	SJ
R I	Scahill	RI
D	Chan	D
R J	Harvey	RJ
N C	Fox	NC
M N	Rossor	MN

Affiliation: Dementia Research Group, Department of Clinical Neurology, Institute of Neurology, Queen Square, London, UK.

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Keywords in this article:

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