Research article summary (published 20 Oct 2002):

Enhancement of use-dependent plasticity by D-amphetamine.

Full Abstract

In healthy individuals, motor training can elicit use-dependent plasticity. Here the authors studied six subjects in whom training alone failed to elicit this effect. Administration of a single dose of 10 mg of D-amphetamine preceding training led to use-dependent plasticity in a subgroup of these subjects. Using pharmacologic interventions to enhance the effects of motor training might help rehabilitative efforts in patients in whom training alone fails.

Learn Faster Today      Improve your study skills

Author information

Author/s: Sawaki, L (L); Cohen, L G (LG); Classen, J (J); Davis, B C (BC); Bütefisch, C M (CM);

Affiliation: Human Cortical Physiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892, USA.

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal: Neurology (Neurology), published in United States. (Language: eng)

Reference: 2002-Oct; vol 59 (issue 8) : pp 1262-4

Dates: Created 2002/10/22; Completed 2002/11/14; Revised 2006/11/15;

PMID: 12391362, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Adult Analysis of Variance Dextroamphetamine - pharmacology Evoked Potentials, Motor - drug effects; physiology Female Hand - physiology

Hand - physiology Humans Male Motor Skills - drug effects; physiology Movement - drug effects; physiology Neuronal Plasticity - drug effects; physiology

Associated Chemicals: Dextroamphetamine (51-64-9)

Related articles

This article has not been indexed for related articles as yet, however you can still use the live related article search links below.

See 100+ related articles.

See a large map of 100+ related articles.