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| Research article summary (published 30 May 2002): |
Electromyographical differentiation between the acoustic blink and startle reflex. Implications for studies investigating startle behavior.
Full Abstract
Recent evidence suggests that electromyographic activity in the orbicularis oculi muscle occurring in response to sudden acoustic stimuli consists of two overlapping components:
the blink and the startle reflex.The aim of the present study was to identify these two components in acoustically elicited eyeblink responses and to analyze their differential modulation by weak acoustic prepulses. The prevalence, latency and amplitude characteristics of double EMG peaks in pulse-alone and prepulse-pulse trials (PP) with 30 ms and 100 ms interstimulus intervals were assessed in 16 healthy volunteers.EMG responses with two peaks were registered in 42.6 % of the pulse-alone trials and in 56.2 % of the PP30 and 48.7 % of the PP100 trials, respectively. Prepulse inhibition of the amplitude was greater for the second peak (14.2 % (P2) vs. -11.5 % (P1) in PP30 trials; 62.6 % (P2) vs. 32.3 % (P1) in PP100 trials), resulting also in higher P1/P2 amplitude ratios in prepulse-pulse trials (P1/P2:
62.9 % in pulse-alone, 92.6 % in PP30 and 100.1 % in PP100 trials).In conclusion, double peaks are a common phenomenon in human studies of acoustically elicited blink responses. It is postulated that the first peak represents the auditory blink reflex, whereas the second peak corresponds to the startle reflex, which may be more susceptible to prepulse inhibition. This complexity should be taken into account in clinical studies of the modulation of the startle reflex.
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Author information
Author/s: Meincke, Ulrich (U); Mörth, Dina (D); Voss, Tatjana (T); Gouzoulis-Mayfrank, Euphrosyne (E);
Affiliation: Department of Psychiatry and Psychotherapy, Technical University of Aachen, Pauwelsstrasse 30, 52057 Aachen, Germany. umeincke(-atsign-)post.klinikum.rwth-aachen.de
Journal and publication information
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal: European archives of psychiatry and clinical neuroscience (Eur Arch Psychiatry Clin Neurosci), published in Germany. (Language: eng)
Reference: 2002-Jun; vol 252 (issue 3) : pp 141-5
Dates: Created 2002/08/22; Completed 2002/11/15; Revised 2006/11/15;
PMID: 12192473, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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