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| Research article summary (published 23 Oct 2002): |
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Effect of dietary supplements on lean mass and strength gains with resistance exercise: a meta-analysis.
Full Abstract
The purpose of this study was to quantify which dietary supplements augment lean mass and strength gains during resistance training. Peer-reviewed studies between the years 1967 and 2001 were included in the analysis if they met a predetermined set of experimental criteria, among which were at least 3-wk duration and resistance-training 2 or more times a week. Lean mass and strength were normalized for meta-analysis by conversion to percent change per week and by calculating the effect size for each variable. Of the 250 supplements examined, only 6 had more than 2 studies that met the criteria for inclusion in the meta-analysis. Creatine and beta-hydroxy-beta-methylbutyrate (HMB) were found to significantly increase net lean mass gains of 0.36 and 0.28%/wk and strength gains of 1.09 and 1.40%/wk (P < 0.05), respectively. Chromium, dehydroepiandrosterone, androstenedione, and protein did not significantly affect lean gain or strength. In conclusion, two supplements, creatine and HMB, have data supporting their use to augment lean mass and strength gains with resistance training.
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Author information
Author/s: Nissen, Steven L (SL); Sharp, Rick L (RL);
Affiliation: Department of Animal Science, Iowa State University, Ames 50011, USA. nissen(-atsign-)iastate.edu
Journal and publication information
Publication Type: Journal Article; Meta-Analysis
Journal: Journal of applied physiology (Bethesda, Md. : 1985) (J Appl Physiol), published in United States. (Language: eng)
Reference: 2003-Feb; vol 94 (issue 2) : pp 651-9
Dates: Created 2003/01/17; Completed 2003/07/21; Revised 2004/11/17;
PMID: 12433852, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
Comments and Corrections
CommentIn: J Appl Physiol. 2003 Nov;95(5):2180-2; author reply 2182. (PMID: 14555678)
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