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| Research article summary (published 29 Nov 2002): |
ECVAM's activities on computer modelling and integrated testing.
Full Abstract
This paper introduces the basic concepts of quantitative structure-activity relationship (QSAR), expert system and integrated testing strategy, and explains how the analogy between QSARs and prediction models leads naturally to criteria for the validation of QSARs. ECVAM's in-house research programme on QSAR modelling and integrated testing is summarised, along with plans for the validation of QSAR models and expert system rulebases at the European Union level.
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Author information
Author/s: Worth, Andrew P (AP);
Affiliation: ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (VA), Italy.
Journal and publication information
Publication Type: Journal Article; Review
Journal: Alternatives to laboratory animals : ATLA (Altern Lab Anim), published in England. (Language: eng)
Reference: 2002-Dec; vol 30 Suppl 2 (issue ) : pp 133-7
Dates: Created 2003/01/06; Completed 2003/07/09; Revised 2005/11/16;
PMID: 12513665, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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