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| Research article summary (published 30 Dec 2002): |
Ear-canal acoustic admittance and reflectance effects in human neonates. I. Predictions of otoacoustic emission and auditory brainstem responses.
Full Abstract
This report describes the extent to which ear-canal acoustic admittance and energy reflectance (YR) in human neonates (1) predict otoacoustic emission (OAE) levels and auditory brainstem response (ABR) latencies, and (2) classify OAE and ABR responses as present or absent. Analyses are reported on a subset of ears in which hearing screening measurements were obtained previously [Norton et al., Ear. Hear. 21, 348-356 (2000a)]. Tests on 1405 ears included YR, distortion-product OAEs, transient-evoked OAEs, and ABR. Principal components analysis reduced the 33 YR variables to 5-7 factors. OAE levels decreased and ABR latencies increased with increasing high-frequency energy reflectance. Up to 28% of the variance in OAE levels and 12% of the variance in ABR wave-V latencies were explained by these factors. Thus, the YR response indirectly encodes information on inter-ear variations in forward and reverse middle-ear transmission. The YR factors classify OAEs with an area under the relative operating characteristic (ROC) curve as high as 0.79, suggesting that middle-ear dysfunction is partly responsible for the inability to record OAEs in some ears. The YR factors classified ABR responses less well, with ROC areas of 0.64 for predicting wave-V latency and 0.56 for predicting Fsp.
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Author information
Author/s: Keefe, Douglas H (DH); Zhao, Fei (F); Neely, Stephen T (ST); Gorga, Michael P (MP); Vohr, Betty R (BR);
Affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA. keefe(-atsign-)boystown.org
Grants: DC01958 (Agency:United States NIDCD) ; DC03784 (Agency:United States NIDCD)
Journal and publication information
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
Journal: The Journal of the Acoustical Society of America (J Acoust Soc Am), published in United States. (Language: eng)
Reference: 2003-Jan; vol 113 (issue 1) : pp 389-406
Dates: Created 2003/01/31; Completed 2003/03/31; Revised 2007/11/14;
PMID: 12558277, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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