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Research article summary:

Dissecting contributions of prefrontal cortex and fusiform face area to face working memory.

Abstract Extract:
Interactions between prefrontal cortex (PFC) and stimulus-specific visual cortical association areas are hypothesized to mediate visual working memory in behaving monkeys. To clarify the roles for homologous regions in humans, event-related fMRI was used ... (Full abstract text below)

Published 2003Aug in Journal: J Cogn Neurosci (Language : eng)

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This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. J Cogn Neurosci. 2003 Aug;15(6):771-84

Dissecting contributions of prefrontal cortex and fusiform face area to face working memory.

Druzgal TJ, D'Esposito M

University of California, Berkeley, USA.

Interactions between prefrontal cortex (PFC) and stimulus-specific visual cortical association areas are hypothesized to mediate visual working memory in behaving monkeys. To clarify the roles for homologous regions in humans, event-related fMRI was used to assess neural activity in PFC and fusiform face area (FFA) of subjects performing a delay-recognition task for faces. In both PFC and FFA, activity increased parametrically with memory load during encoding and maintenance of face stimuli, despite quantitative differences in the magnitude of activation. Moreover, timing differences in PFC and FFA activation during memory encoding and retrieval implied a context dependence in the flow of neural information. These results support existing neurophysiological models of visual working memory developed in the nonhuman primate.

PMID : 14511531 [PubMed - Indexed for MEDLINE]


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Full Author Information

First NameLastNameInitials
T JasonDruzgalTJ
MarkD'EspositoM

Affiliation: University of California, Berkeley, USA.

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