Research article summary:

Dietary manganese intake and type of lipid do not affect clinical or neuropsychological measures in healthy young women.

Abstract Extract:
Because manganese (Mn) is potentially toxic, and because dietary fat type may affect Mn absorption, the objectives of the current study were to determine whether diets containing very low or very high amounts of Mn and enriched in either saturated or ... (Full abstract text below)

Published 2003Sep in Journal: J Nutr (Language : eng)

Full Pubmed Extract

This information was retrieved, real-time, on your behalf from the public area of the Pubmed website:

1. J Nutr. 2003 Sep;133(9):2849-56

Dietary manganese intake and type of lipid do not affect clinical or neuropsychological measures in healthy young women.

Finley JW, Penland JG, Pettit RE, Davis CD

US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND, USA. jfinley@gfhnrc.ars.usda.gov

Because manganese (Mn) is potentially toxic, and because dietary fat type may affect Mn absorption, the objectives of the current study were to determine whether diets containing very low or very high amounts of Mn and enriched in either saturated or unsaturated fats affected measures of neuropsychological and basic metabolic function. Healthy young women were fed for 8 wk each, in a crossover design, diets that provided 0.8 or 20 mg of Mn/d. One half of the subjects received 15% of energy as cocoa butter, and one half received 15% of energy as corn oil. A meal containing (54)Mn was fed after 4 wk, and subjects underwent whole-body counting for the next 21 d. Blood draws and neuropsychological tests were administered at regular intervals during the dietary periods. When subjects consumed the diets low in Mn, compared with the high Mn diets, they absorbed a significantly higher percentage of (54)Mn, but had a significantly longer biological half-life of the absorbed (54)Mn. Manganese intake did not affect any neurological measures and only minimally affected psychologic variables. These data show that efficient mechanisms operate to maintain Mn homeostasis over the range of intakes that may be encountered in a mixed Western diet. Thus, dietary intakes of Mn from 0.8 to 20 mg for 8 wk likely do not result in Mn deficiency or toxicity signs in healthy adults.

PMID : 12949376 [PubMed - Indexed for MEDLINE]

This information is obtained from the National Library of Medicine (NLM). Abstract text and other information may be subject to copyright. Type "NLM copyright" into Google for more information.

Full Author Information

First Name	LastName	Initials
John W	Finley	JW
James G	Penland	JG
Ross E	Pettit	RE
Cindy D	Davis	CD

Affiliation: US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND, USA. jfinley@gfhnrc.ars.usda.gov

3rd Party provider links

Click the links below to go to related 3rd party information:

MESH categories and related page links

This article was linked to the MESH categories shown on the left below. The links on the right are related Memletics pages.

Links for this article

For links to places where you can get the full text of this article see links. Note there may be a subscription or fee required for access to the full text.

New! Using similar technology to this site, we have launched find-health-articles.com, targeting over 1 million health research article abstracts.

Here are some articles related to this one (by title keywords):

Uses and limitations of statistical accounting for random error correlations, in the validation of dietary questionnaire assessments.

Unaltered brain levels of 1,N2-propanodeoxyguanosine adducts of trans-4-hydroxy-2-nonenal in Alzheimers disease.

Snacking patterns influence energy and nutrient intakes but not body mass index.

Implications of day-to-day variability on measurements of usual food and nutrient intakes.

Comparison of two instruments for quantifying intake of vitamin and mineral supplements: a brief questionnaire versus three 24-hour recalls.

Assessment and significance of 24-h energy intake patterns among young and aged non-affluent southern US women.

Affect optimization and affect complexity: modes and styles of regulation in adulthood.

Accuracy of fourth-graders dietary recalls of school breakfast and school lunch validated with observations: in-person versus telephone interviews.

Validity of childrens food portion estimates: a comparison of 2 measurement aids.

An evaluation of the sensitivity and specificity of energy expenditure measured by heart rate and the Goldberg cut-off for energy intake: basal metabolic rate for identifying mis-reporting of energy intake by adults and children: a retrospective analysis.

>>> Get more research article abstracts like these, or browse abstracts.

Keywords in this article:

absorbed, absorption, administered, affect, affected, after, amounts, basic, biological, blood, body, butter, cocoa, compared, consumed, containing, corn, counting, crossover, current, data, deficiency, design, determine, dietary, diets, draws, efficient, encountered, energy, enriched, fat, fats, fed, function, half, healthy, high, higher, homeostasis, intake, intakes, intervals, life, likely, longer, low, maintain, manganese, meal, measures, mechanisms, metabolic, minimally, mixed, mn, neurological, neuropsychological, next, not, objectives, oil, one, only, operate, percentage, periods, potentially, provided, range, received, regular, result, saturated, signs, study, subjects, tests, toxic, toxicity, type, underwent, unsaturated, variables, western, whether, whole, wk, women, young

Also, see our new free speed reading online course (beta version)