A computational model of anterior cingulate function in speeded response tasks: effects of frequency, sequence, and conflict.

Full Abstract

A growing body of evidence from functional neuroimaging and computational modeling studies indicates that the anterior cingulate cortex (ACC) detects the presence of response conflict and conveys this information to other brain regions, enabling subsequent adjustments in cognitive control. The present study examined previous empirical findings of increased ACC for low-frequency stimuli across three distinct speeded response tasks (two-alternative forced choice, go/no-go, and oddball). Simulations conducted in a neural network model incorporating sequential priming mechanisms (developed in Cho et al., 2002) confirmed that a computational measure of response conflict was higher on low-frequency trials across all three tasks. In addition, the model captured detailed aspects of behavioral reaction time and accuracy data, predicted the dynamics of ACC activity related to trial sequence effects, and provided evidence for the functional role of conflict information in performance monitoring and optimization. The results indicate that the conflict-monitoring hypothesis, augmented by mechanisms for encoding stimulus history, can explain key phenomena associated with performance in sequential speeded response tasks.

Learn Faster Today Improve your study skills

Author information

Author/s: Jones, Andrew D (AD); Cho, Raymond Y (RY); Nystrom, Leigh E (LE); Cohen, Jonathan D (JD); Braver, Todd S (TS);

Affiliation: Washington University, St. Louis, Missouri 63130, USA.

Grants: P50 MH62196 (Agency:NIMH NIH HHS)

Journal and publication information

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal: Cognitive, affective & behavioral neuroscience (Cogn Affect Behav Neurosci), published in United States. (Language: eng)

Reference: 2002-Dec; vol 2 (issue 4) : pp 300-17

Dates: Created 2003/03/18; Completed 2003/04/07; Revised 2007/11/14;

PMID: 12641175, status: MEDLINE (last retrieval date: 12/26/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

External Links for this article (including full text providers, if available):

Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.

This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.

MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Humans
Magnetic Resonance Imaging
Male
Neural Networks (Computer)
Psychomotor Performance - physiology
Reaction Time - physiology
Task Performance and Analysis

These are the highest related articles currently in the database:

See 100+ related articles.