 |
| Research article summary (published 30 Dec 2002): |
Competition among multiple memory systems: converging evidence from animal and human brain studies.
Full Abstract
Research of the neurobiological bases of learning and memory suggest that these processes are not unitary in nature, but rather that relatively independent neural systems appear to mediate different types of memory. Neurobiological studies, for instance, have identified separable cognitive or "declarative" and stimulus-response "habit" memory systems that rely upon the medial temporal lobe (e.g. hippocampus) and basal ganglia (e.g. caudate-putamen), respectively. Evidence indicates that multiple memory systems are activated simultaneously and in parallel in various learning tasks, and recent findings suggest that these systems may interact. One form of interaction between medial temporal lobe and basal ganglia memory systems appears competitive in nature, and has been revealed in non-human animal studies in which damage to a given memory system results in enhanced learning. Recent human neuroimaging research has also provided evidence in favor of competition between memory systems. Thus, converging evidence across species supports the hypothesis of interactive multiple memory systems in the mammalian brain. Potential neurobiological mechanisms mediating such interactions include direct anatomical projections between the medial temporal lobe and basal ganglia, indirect neuromodulatory influences of other brain structures (e.g. basolateral amygdala) and activity of neocortical brain regions involved in top-down response selection.
Learn Faster Today Improve your study skills
Author information
Author/s: Poldrack, Russell A (RA); Packard, Mark G (MG);
Affiliation: Department of Psychology and Brain Research Institute, Franz Hall, University of California at Los Angeles, PO Box 951563, Los Angeles, CA 90095-1563, USA. poldrack(-atsign-)ucla.edu
Journal and publication information
Publication Type: Journal Article; Review
Journal: Neuropsychologia (Neuropsychologia), published in England. (Language: eng)
Reference: 2003-; vol 41 (issue 3) : pp 245-51
Dates: Created 2002/11/29; Completed 2003/03/05; Revised 2005/11/16;
PMID: 12457750, status: MEDLINE (last retrieval date: 11/6/2008)
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
Comments and Corrections
CommentIn: Neuropsychologia. 2003;41(3):241-4. (PMID: 12457749)
External Links for this article (including full text providers, if available):
Click Electronic Full-text Provider Links to see options for finding the electronic full text links to this article. Note there may be a subscription or fee required for access to the full text. See our FAQ for information on finding FREE full text articles.
This article may also be located in paper journal collections available in many libraries. Use the Journal and Publication Information above to find the full article.
MeSH headings (categories)
This article was linked to the MESH Headings shown below.
|
|
Related articles
This article has not been indexed for related articles as yet, however you can still use the live related article search links below.
See a large map of 100+ related articles.