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Research article summary (published 29 Sep 2002):

A comparative study of sevoflurane sedation with nitrous oxide sedation for dental surgery.

Full Abstract

This study compares the use of inhalation sedation using sevoflurane (group S) with inhalation sedation using nitrous oxide (group N) in patients undergoing bilateral extraction of third molar teeth under local anaesthesia. The study was designed as a cross-over study. Seventeen ASA I, day surgery patients were studied. Patients were randomly allocated to receive either 8 l/min 50% nitrous oxide in oxygen (group N) or same flow of 1% sevoflurane (group S) for the first procedure. Each patient then had the alternate method of sedation for the second procedure. There were no significant differences between the methods in patient co-operation and surgeon's satisfaction with sedation. Psychomotor tests were comparable in both groups. The patients were significantly more sedated in the group S compared to group N (P=0.004). Significantly more patients complained of an unpleasant odour group S (P<0.01) but none withdrew from the study for this reason. No adverse cardiorespiratory effects resulted from sevoflurane or nitrous oxide sedation. Both methods gave good amnesia during the procedure. There was high acceptance of both methods and the patients rated the technique as equally satisfactory. We conclude that inhalation sedation with sevoflurane is a suitable alternative method to nitrous oxide sedation.

 

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Author information

Author/s: Wang, C Y (CY); Chiu, C L (CL); Har, K O (KO); Chan, C (C); Rahman, Z A A (ZA);

Affiliation: Department of Anaesthesia, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. wangcy(-atsign-)ummc.edu.my

Journal and publication information

Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial

Journal: International journal of oral and maxillofacial surgery (Int J Oral Maxillofac Surg), published in Denmark. (Language: eng)

Reference: 2002-Oct; vol 31 (issue 5) : pp 506-10

Dates: Created 2002/11/06; Completed 2003/01/21; Revised 2007/11/15;

PMID: 12418566, status: MEDLINE (last retrieval date: 11/6/2008)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Associated Chemicals: Anesthetics, Inhalation (0) ; Methyl Ethers (0) ; Nitrous Oxide (10024-97-2) ; sevoflurane (28523-86-6)

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